Explore TRPC6 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]
| Target ID |
GM-T80165
|
| Target Name |
TRPC6
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7225
|
| Gene ID |
100061175 (Equus caballus), 101082685 (Felis catus), 22068 (Mus musculus), 407151 (Bos taurus)
489435 (Canis lupus familiaris), 703611 (Macaca mulatta), 7225 (Homo sapiens), 89823 (Rattus norvegicus)
|
| Target Alternative Names |
FSGS2,LLHWJM002,LLHWJM003,LLHWJM004,Short transient receptor potential channel 6,TRP-6,TRP6,TRPC6,Transient receptor protein 6 (TRP-6),TrpC6,Trpc6,Trrp6,mtrp6,trp6
|
| Uniprot Accession |
Q61143,Q9MYW0,Q9Y210
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
cGMP-PKG signaling pathway, Axon guidance
|
| Gene Ensembl |
ENSECAG00000023421, ENSMUSG00000031997, ENSBTAG00000011227, ENSCAFG00845001326, ENSMMUG00000011835, ENSG00000137672
|
| Target Classification |
|
Pre-made viral vector of TRPC6 cDNA Clones/ORF Plasmid
TRPC6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7225 | Pre-made Human TRPC6/TRP6/FSGS2 siRNA oligo Duplex | 7225 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo89823 | Pre-made Rat Trpc6/Trrp6 siRNA oligo Duplex | 89823 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22068 | Pre-made Mouse Trpc6/TRP-6/Trrp6 siRNA oligo Duplex | 22068 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703611 | Pre-made Cynomolgus/Rhesus macaque TRPC6 siRNA oligo Duplex | 703611 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082685 | Pre-made Cat/Feline TRPC6 siRNA oligo Duplex | 101082685 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489435 | Pre-made Dog/Canine TRPC6 siRNA oligo Duplex | 489435 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407151 | Pre-made Bovines/Cattle TRPC6/trp6 siRNA oligo Duplex | 407151 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061175 | Pre-made Equine/Horse TRPC6 siRNA oligo Duplex | 100061175 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TRPC6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T80165-Ab | Human | Anti-Human TRPC6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T80165-Ab | Rat | Anti-Rat TRPC6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T80165-Ab | Mouse | Anti-Mouse TRPC6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T80165-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TRPC6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T80165-Ab | Cat/Feline | Anti-Cat/Feline TRPC6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T80165-Ab | Dog/Canine | Anti-Dog/Canine TRPC6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T80165-Ab | Bovines/Cattle | Anti-Bovines/Cattle TRPC6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T80165-Ab | Equine/Horse | Anti-Equine/Horse TRPC6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TRPC6 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T80165-Ag | Human | Human TRPC6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T80165-Ag | Rat | Rat TRPC6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T80165-Ag | Mouse | Mouse TRPC6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T80165-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TRPC6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T80165-Ag | Cat/Feline | Cat/Feline TRPC6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T80165-Ag | Dog/Canine | Dog/Canine TRPC6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T80165-Ag | Bovines/Cattle | Bovines/Cattle TRPC6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T80165-Ag | Equine/Horse | Equine/Horse TRPC6 VLP (virus-like particle) | HEK293 | Products Developing |
