Explore L1CAM/CD171 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]
| Target ID |
GM-T80020
|
| Target Name |
L1CAM/CD171
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3897
|
| Gene ID |
100059024 (Equus caballus), 101088733 (Felis catus), 16728 (Mus musculus), 3897 (Homo sapiens)
492244 (Canis lupus familiaris), 50687 (Rattus norvegicus), 516017 (Bos taurus), 697504 (Macaca mulatta)
|
| Target Alternative Names |
CAML1,CD171,HSAS,HSAS1,HYCX,Hsas,Hyd,L1,L1CAM,L1cam,MASA,MIC5,N-CAM L1,N-CAM-L1,N-CAML1,NCAM-L1,NCAML1,Neural cell adhesion molecule L1,NgCAM,S10,SPG1
|
| Uniprot Accession |
P11627,P32004,Q05695
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer, Prostate Cancer, Renal tubulo-interstitial diseases
|
| Disease from KEGG |
Axon guidance, Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000002810, ENSMUSG00000031391, ENSG00000198910, ENSCAFG00845025647, ENSBTAG00000013462, ENSMMUG00000003379
|
| Target Classification |
Checkpoint-Immuno Oncology
|
L1CAM/CD171 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3897 | Pre-made Human L1CAM/S10/HSAS siRNA oligo Duplex | 3897 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50687 | Pre-made Rat L1cam/Hyd/Hsas siRNA oligo Duplex | 50687 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16728 | Pre-made Mouse L1cam/L1/CD171 siRNA oligo Duplex | 16728 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697504 | Pre-made Cynomolgus/Rhesus macaque L1CAM siRNA oligo Duplex | 697504 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088733 | Pre-made Cat/Feline L1CAM siRNA oligo Duplex | 101088733 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo492244 | Pre-made Dog/Canine L1CAM siRNA oligo Duplex | 492244 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo516017 | Pre-made Bovines/Cattle L1CAM siRNA oligo Duplex | 516017 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059024 | Pre-made Equine/Horse L1CAM siRNA oligo Duplex | 100059024 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
L1CAM/CD171 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T80020-Ab | Human | Anti-Human L1CAM/CD171 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T80020-Ab | Rat | Anti-Rat L1CAM/CD171 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T80020-Ab | Mouse | Anti-Mouse L1CAM/CD171 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T80020-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque L1CAM/CD171 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T80020-Ab | Cat/Feline | Anti-Cat/Feline L1CAM/CD171 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T80020-Ab | Dog/Canine | Anti-Dog/Canine L1CAM/CD171 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T80020-Ab | Bovines/Cattle | Anti-Bovines/Cattle L1CAM/CD171 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T80020-Ab | Equine/Horse | Anti-Equine/Horse L1CAM/CD171 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
L1CAM/CD171 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T80020-Ag | Human | Human L1CAM/CD171 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T80020-Ag | Rat | Rat L1CAM/CD171 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T80020-Ag | Mouse | Mouse L1CAM/CD171 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T80020-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque L1CAM/CD171 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T80020-Ag | Cat/Feline | Cat/Feline L1CAM/CD171 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T80020-Ag | Dog/Canine | Dog/Canine L1CAM/CD171 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T80020-Ag | Bovines/Cattle | Bovines/Cattle L1CAM/CD171 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T80020-Ag | Equine/Horse | Equine/Horse L1CAM/CD171 VLP (virus-like particle) | HEK293 | Products Developing |
