Explore LHCGR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T79473
|
| Target Name |
LHCGR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3973
|
| Gene ID |
100034043 (Equus caballus), 101088154 (Felis catus), 16867 (Mus musculus), 25477 (Rattus norvegicus)
281900 (Bos taurus), 3973 (Homo sapiens), 481365 (Canis lupus familiaris), 715999 (Macaca mulatta)
|
| Target Alternative Names |
Gpcr19-rs1,HHG,LCGR,LGR2,LH-R,LH/CG-R,LH/CGR,LHCGR,LHR,LHRHR,LSH-R,LSH-R),LSHR,Lhcgr,Lhr,Luteinizing hormone receptor (LHR,Lutropin-choriogonadotropic hormone receptor,ULG5
|
| Uniprot Accession |
P30730,P16235,Q28005,P22888
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Prolactin signaling pathway
|
| Gene Ensembl |
ENSECAG00000020677, ENSMUSG00000024107, ENSBTAG00000016573, ENSG00000138039, ENSCAFG00845006174, ENSMMUG00000010368
|
| Target Classification |
GPCR, Tumor-associated antigen (TAA)
|
LHCGR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3973 | Pre-made Human LHCGR/HHG/LHR siRNA oligo Duplex | 3973 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25477 | Pre-made Rat Lhcgr/Lhr/LSHR siRNA oligo Duplex | 25477 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16867 | Pre-made Mouse Lhcgr/Lhr/LH-R siRNA oligo Duplex | 16867 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715999 | Pre-made Cynomolgus/Rhesus macaque LHCGR siRNA oligo Duplex | 715999 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088154 | Pre-made Cat/Feline LHCGR siRNA oligo Duplex | 101088154 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481365 | Pre-made Dog/Canine LHCGR/LHR siRNA oligo Duplex | 481365 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281900 | Pre-made Bovines/Cattle LHCGR siRNA oligo Duplex | 281900 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034043 | Pre-made Equine/Horse LHCGR siRNA oligo Duplex | 100034043 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LHCGR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T79473-Ab | Human | Anti-Human LHCGR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T79473-Ab | Rat | Anti-Rat LHCGR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T79473-Ab | Mouse | Anti-Mouse LHCGR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T79473-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LHCGR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T79473-Ab | Cat/Feline | Anti-Cat/Feline LHCGR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T79473-Ab | Dog/Canine | Anti-Dog/Canine LHCGR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T79473-Ab | Bovines/Cattle | Anti-Bovines/Cattle LHCGR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T79473-Ab | Equine/Horse | Anti-Equine/Horse LHCGR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LHCGR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T79473-Ag | Human | Human LHCGR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T79473-Ag | Rat | Rat LHCGR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T79473-Ag | Mouse | Mouse LHCGR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T79473-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LHCGR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T79473-Ag | Cat/Feline | Cat/Feline LHCGR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T79473-Ag | Dog/Canine | Dog/Canine LHCGR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T79473-Ag | Bovines/Cattle | Bovines/Cattle LHCGR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T79473-Ag | Equine/Horse | Equine/Horse LHCGR VLP (virus-like particle) | HEK293 | Products Developing |
