Explore KLK4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Several transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Dec 2014]
| Target ID |
GM-T79400
|
| Target Name |
KLK4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9622
|
| Gene ID |
101089560 (Felis catus), 408210 (Rattus norvegicus), 484354 (Canis lupus familiaris), 507800 (Bos taurus)
56640 (Mus musculus), 719422 (Macaca mulatta), 9622 (Homo sapiens)
|
| Target Alternative Names |
AI2A1,ARM1,EMSP,EMSP1,ESMP1,Emsp1,Enamel matrix serine proteinase 1,KLK-L1,KLK4,KLNB1,Kallikrein-4,Kallikrein-like protein 1 (KLK-L1),Klk4,Klnb1,PRSS17,PSTS,Prostase,Prss17,Serine protease 17,kallikrein
|
| Uniprot Accession |
Q9Z0M1,Q9Y5K2
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSBTAG00000020415, ENSMUSG00000006948, ENSMMUG00000028729, ENSG00000167749
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of KLK4 cDNA Clones/ORF Plasmid
KLK4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9622 | Pre-made Human KLK4/ARM1/EMSP siRNA oligo Duplex | 9622 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo408210 | Pre-made Rat Klk4/Emsp1/Klnb1 siRNA oligo Duplex | 408210 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56640 | Pre-made Mouse Klk4/PSTS/ESMP1 siRNA oligo Duplex | 56640 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719422 | Pre-made Cynomolgus/Rhesus macaque KLK4 siRNA oligo Duplex | 719422 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089560 | Pre-made Cat/Feline KLK4 siRNA oligo Duplex | 101089560 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484354 | Pre-made Dog/Canine KLK4 siRNA oligo Duplex | 484354 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507800 | Pre-made Bovines/Cattle KLK4/KLNB1 siRNA oligo Duplex | 507800 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
KLK4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T79400-Ab | Human | Anti-Human KLK4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T79400-Ab | Rat | Anti-Rat KLK4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T79400-Ab | Mouse | Anti-Mouse KLK4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T79400-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KLK4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T79400-Ab | Cat/Feline | Anti-Cat/Feline KLK4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T79400-Ab | Dog/Canine | Anti-Dog/Canine KLK4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T79400-Ab | Bovines/Cattle | Anti-Bovines/Cattle KLK4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KLK4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T79400-Ag | Human | Human KLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T79400-Ag | Rat | Rat KLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T79400-Ag | Mouse | Mouse KLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T79400-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T79400-Ag | Cat/Feline | Cat/Feline KLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T79400-Ag | Dog/Canine | Dog/Canine KLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T79400-Ag | Bovines/Cattle | Bovines/Cattle KLK4 recombinant protein | Mammalian cell | Detail |
