Explore ULK1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Enables identical protein binding activity; protein serine/threonine kinase activity; and small GTPase binding activity. Involved in several processes, including autophagosome assembly; positive regulation by symbiont of host autophagy; and protein phosphorylation. Located in autophagosome; cytosol; and phagophore assembly site membrane. Is extrinsic component of autophagosome membrane; extrinsic component of omegasome membrane; and extrinsic component of phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T79307
|
| Target Name |
ULK1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8408
|
| Gene ID |
101098658 (Felis catus), 138915231 (Equus caballus), 22241 (Mus musculus), 360827 (Rattus norvegicus) 477437 (Canis lupus familiaris), 526310 (Bos taurus), 709746 (Macaca mulatta), 8408 (Homo sapiens)
|
| Target Alternative Names |
ATG1,ATG1A,Autophagy-related protein 1 homolog (ATG1,Serine/threonine-protein kinase ULK1,ULK1,UNC51,Ulk1,Unc-51-like kinase 1,Unc51.1,hATG1,hATG1),mKIAA0722
|
| Uniprot Accession |
O70405,O75385
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Longevity regulating pathway, Alzheimer disease
|
| Gene Ensembl |
ENSMUSG00000029512, ENSCAFG00845028856, ENSBTAG00000012987, ENSMMUG00000015773, ENSG00000177169
|
| Target Classification |
Kinase
|
Pre-made viral vector of ULK1 cDNA Clones/ORF Plasmid
ULK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8408 | Pre-made Human ULK1/ATG1/ATG1A siRNA oligo Duplex | 8408 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360827 | Pre-made Rat Ulk1 siRNA oligo Duplex | 360827 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22241 | Pre-made Mouse Ulk1/Unc51.1/mKIAA0722 siRNA oligo Duplex | 22241 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709746 | Pre-made Cynomolgus/Rhesus macaque ULK1 siRNA oligo Duplex | 709746 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098658 | Pre-made Cat/Feline ULK1 siRNA oligo Duplex | 101098658 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477437 | Pre-made Dog/Canine ULK1 siRNA oligo Duplex | 477437 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo526310 | Pre-made Bovines/Cattle ULK1 siRNA oligo Duplex | 526310 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo138915231 | Pre-made Equine/Horse ULK1 siRNA oligo Duplex | 138915231 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ULK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T79307-Ab | Human | Anti-Human ULK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T79307-Ab | Rat | Anti-Rat ULK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T79307-Ab | Mouse | Anti-Mouse ULK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T79307-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ULK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T79307-Ab | Cat/Feline | Anti-Cat/Feline ULK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T79307-Ab | Dog/Canine | Anti-Dog/Canine ULK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T79307-Ab | Bovines/Cattle | Anti-Bovines/Cattle ULK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T79307-Ab | Equine/Horse | Anti-Equine/Horse ULK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ULK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T79307-Ag | Human | Human ULK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T79307-Ag | Rat | Rat ULK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T79307-Ag | Mouse | Mouse ULK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T79307-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ULK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T79307-Ag | Cat/Feline | Cat/Feline ULK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T79307-Ag | Dog/Canine | Dog/Canine ULK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T79307-Ag | Bovines/Cattle | Bovines/Cattle ULK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T79307-Ag | Equine/Horse | Equine/Horse ULK1 recombinant protein | Mammalian cell | Detail |