Explore KCNJ1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T78710
|
| Target Name |
KCNJ1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3758
|
| Gene ID |
100072580 (Equus caballus), 101091140 (Felis catus), 24521 (Rattus norvegicus), 3758 (Homo sapiens)
489285 (Canis lupus familiaris), 539250 (Bos taurus), 56379 (Mus musculus), 714848 (Macaca mulatta)
|
| Target Alternative Names |
ATP-regulated potassium channel ROM-K,ATP-sensitive inward rectifier potassium channel 1,Inward rectifier K(+) channel Kir1.1,KAB-1,KCNJ1,KIR1.1,Kcnj,Kcnj1,Kcnj1_v1,Kcnj1_v3,Kir1.1,Potassium channel,ROMK,ROMK1,ROMK2,ROMK3,Romk2,inwardly rectifying subfamily J member 1,kir1.1
|
| Uniprot Accession |
P35560,P48048,O88335
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Aldosterone-regulated sodium reabsorption, Gastric acid secretion
|
| Gene Ensembl |
ENSECAG00000024963, ENSG00000151704, ENSBTAG00000000008, ENSMUSG00000041248, ENSMMUG00000003144
|
Pre-made viral vector of KCNJ1 cDNA Clones/ORF Plasmid
KCNJ1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3758 | Pre-made Human KCNJ1/ROMK/ROMK1 siRNA oligo Duplex | 3758 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24521 | Pre-made Rat Kcnj1/Kcnj/KAB-1 siRNA oligo Duplex | 24521 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56379 | Pre-made Mouse Kcnj1/ROMK/Romk2 siRNA oligo Duplex | 56379 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714848 | Pre-made Cynomolgus/Rhesus macaque KCNJ1 siRNA oligo Duplex | 714848 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091140 | Pre-made Cat/Feline KCNJ1 siRNA oligo Duplex | 101091140 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489285 | Pre-made Dog/Canine KCNJ1 siRNA oligo Duplex | 489285 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539250 | Pre-made Bovines/Cattle KCNJ1 siRNA oligo Duplex | 539250 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072580 | Pre-made Equine/Horse KCNJ1 siRNA oligo Duplex | 100072580 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNJ1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T78710-Ab | Human | Anti-Human KCNJ1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T78710-Ab | Rat | Anti-Rat KCNJ1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T78710-Ab | Mouse | Anti-Mouse KCNJ1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T78710-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNJ1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T78710-Ab | Cat/Feline | Anti-Cat/Feline KCNJ1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T78710-Ab | Dog/Canine | Anti-Dog/Canine KCNJ1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T78710-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNJ1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T78710-Ab | Equine/Horse | Anti-Equine/Horse KCNJ1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KCNJ1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T78710-Ag | Human | Human KCNJ1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T78710-Ag | Rat | Rat KCNJ1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T78710-Ag | Mouse | Mouse KCNJ1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T78710-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNJ1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T78710-Ag | Cat/Feline | Cat/Feline KCNJ1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T78710-Ag | Dog/Canine | Dog/Canine KCNJ1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T78710-Ag | Bovines/Cattle | Bovines/Cattle KCNJ1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T78710-Ag | Equine/Horse | Equine/Horse KCNJ1 VLP (virus-like particle) | HEK293 | Products Developing |
