Explore HTR1A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
| Target ID |
GM-T78709
|
| Target Name |
HTR1A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3350
|
| Gene ID |
100009683 (Equus caballus), 101101542 (Felis catus), 15550 (Mus musculus), 24473 (Rattus norvegicus) 3350 (Homo sapiens), 407137 (Bos taurus), 487230 (Canis lupus familiaris), 694991 (Macaca mulatta)
|
| Target Alternative Names |
5-HT-1A,5-HT1A,5-hydroxytryptamine receptor 1A,5HT1A,5HT1a,5htr1a,ADRB2RL1,ADRBRL1,G-21,Gpcr18,HTR1A,Htr1a,PFMCD,RAT5HT1A,Serotonin receptor 1A
|
| Uniprot Accession |
Q0EAB6,Q64264,P19327,P08908,Q6XXX9
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction
|
| Gene Ensembl |
ENSECAG00000028607, ENSMUSG00000021721, ENSG00000178394, ENSBTAG00000040439, ENSMMUG00000001789
|
| Target Classification |
GPCR
|
Pre-made viral vector of HTR1A cDNA Clones/ORF Plasmid
HTR1A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3350 | Pre-made Human HTR1A/G-21/5HT1a siRNA oligo Duplex | 3350 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24473 | Pre-made Rat Htr1a/5HT1A/RAT5HT1A siRNA oligo Duplex | 24473 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15550 | Pre-made Mouse Htr1a/Gpcr18 siRNA oligo Duplex | 15550 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694991 | Pre-made Cynomolgus/Rhesus macaque HTR1A/5-HT1A siRNA oligo Duplex | 694991 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101542 | Pre-made Cat/Feline HTR1A siRNA oligo Duplex | 101101542 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487230 | Pre-made Dog/Canine HTR1A siRNA oligo Duplex | 487230 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407137 | Pre-made Bovines/Cattle HTR1A/5HT1A/5htr1a siRNA oligo Duplex | 407137 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009683 | Pre-made Equine/Horse HTR1A/5-HT1A/5-HT-1A siRNA oligo Duplex | 100009683 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HTR1A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T78709-Ab | Human | Anti-Human HTR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T78709-Ab | Rat | Anti-Rat HTR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T78709-Ab | Mouse | Anti-Mouse HTR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T78709-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HTR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T78709-Ab | Cat/Feline | Anti-Cat/Feline HTR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T78709-Ab | Dog/Canine | Anti-Dog/Canine HTR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T78709-Ab | Bovines/Cattle | Anti-Bovines/Cattle HTR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T78709-Ab | Equine/Horse | Anti-Equine/Horse HTR1A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HTR1A VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T78709-Ag | Human | Human HTR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T78709-Ag | Rat | Rat HTR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T78709-Ag | Mouse | Mouse HTR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T78709-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HTR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T78709-Ag | Cat/Feline | Cat/Feline HTR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T78709-Ag | Dog/Canine | Dog/Canine HTR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T78709-Ag | Bovines/Cattle | Bovines/Cattle HTR1A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T78709-Ag | Equine/Horse | Equine/Horse HTR1A VLP (virus-like particle) | HEK293 | Products Developing |