Explore OSMR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
| Target ID |
GM-T78567
|
| Target Name |
OSMR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9180
|
| Gene ID |
100066819 (Equus caballus), 101096447 (Felis catus), 18414 (Mus musculus), 310132 (Rattus norvegicus)
489223 (Canis lupus familiaris), 514720 (Bos taurus), 693569 (Macaca mulatta), 9180 (Homo sapiens)
|
| Target Alternative Names |
IL-31R subunit beta,IL-31R-beta,IL-31RB,IL-31RB),Interleukin-31 receptor subunit beta (IL-31 receptor subunit beta,OSMR,OSMRB,OSMRbeta,Oncostatin-M-specific receptor subunit beta,Osmr,PLCA1
|
| Uniprot Accession |
O70458,Q65Z14,Q99650
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway
|
| Gene Ensembl |
ENSECAG00000019438, ENSMUSG00000022146, ENSCAFG00845003423, ENSBTAG00000033107, ENSMMUG00000001609, ENSG00000145623
|
| Target Classification |
Cytokine Receptor
|
OSMR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9180 | Pre-made Human OSMR/OSMRB/PLCA1 siRNA oligo Duplex | 9180 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo310132 | Pre-made Rat Osmr siRNA oligo Duplex | 310132 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18414 | Pre-made Mouse Osmr/OSMRB siRNA oligo Duplex | 18414 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693569 | Pre-made Cynomolgus/Rhesus macaque OSMR siRNA oligo Duplex | 693569 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096447 | Pre-made Cat/Feline OSMR siRNA oligo Duplex | 101096447 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489223 | Pre-made Dog/Canine OSMR siRNA oligo Duplex | 489223 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514720 | Pre-made Bovines/Cattle OSMR siRNA oligo Duplex | 514720 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066819 | Pre-made Equine/Horse OSMR siRNA oligo Duplex | 100066819 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OSMR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T78567-Ab | Human | Anti-Human OSMR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T78567-Ab | Rat | Anti-Rat OSMR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T78567-Ab | Mouse | Anti-Mouse OSMR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T78567-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OSMR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T78567-Ab | Cat/Feline | Anti-Cat/Feline OSMR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T78567-Ab | Dog/Canine | Anti-Dog/Canine OSMR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T78567-Ab | Bovines/Cattle | Anti-Bovines/Cattle OSMR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T78567-Ab | Equine/Horse | Anti-Equine/Horse OSMR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
OSMR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T78567-Ag | Human | Human OSMR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T78567-Ag | Rat | Rat OSMR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T78567-Ag | Mouse | Mouse OSMR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T78567-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OSMR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T78567-Ag | Cat/Feline | Cat/Feline OSMR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T78567-Ag | Dog/Canine | Dog/Canine OSMR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T78567-Ag | Bovines/Cattle | Bovines/Cattle OSMR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T78567-Ag | Equine/Horse | Equine/Horse OSMR VLP (virus-like particle) | HEK293 | Products Developing |
