Explore CD44 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T78319
|
| Target Name |
CD44
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
960
|
| Gene ID |
100034221 (Equus caballus), 101098744 (Felis catus), 12505 (Mus musculus), 25406 (Rattus norvegicus) 281057 (Bos taurus), 403939 (Canis lupus familiaris), 717204 (Macaca mulatta), 960 (Homo sapiens)
|
| Target Alternative Names |
CD44,CD44 antigen,CD44A,CDW44,CDw44,CSPG8,Cd44,ECM-III,ECMR-III,Epican,Extracellular matrix receptor III (ECMR-III),GP90 lymphocyte homing/adhesion receptor,H-CAM,HCELL,HERMES,HUTCH-1,HUTCH-I,Heparan sulfate proteoglycan,Hermes antigen,Hermes-1,Hyaluronate receptor,IN,LHR,Ly-24,MC56,MDU2,MDU3,METAA,MIC4,Pgp-1,Pgp1,Phagocytic glycoprotein 1 (PGP-1),Phagocytic glycoprotein I (PGP-I),RHAMM
|
| Uniprot Accession |
Q05078,P15379,P26051,Q29423,Q28284,P16070
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer, colon cancer, Malignant neoplasm of bladder, Congenital occlusion of ureteropelvic junction, IgA glomerulonephritis, Lung cancer
|
| Disease from KEGG |
ECM-receptor interaction, Hematopoietic cell lineage, Epstein-Barr virus infection, Proteoglycans in cancer
|
| Gene Ensembl |
ENSECAG00000010267, ENSMUSG00000005087, ENSBTAG00000011578, ENSCAFG00845022357, ENSMMUG00000004327, ENSG00000026508
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of CD44 cDNA Clones/ORF Plasmid
CD44 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo960 | Pre-made Human CD44/IN/LHR siRNA oligo Duplex | 960 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25406 | Pre-made Rat Cd44/CD44A/METAA siRNA oligo Duplex | 25406 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12505 | Pre-made Mouse Cd44/Ly-24/Pgp-1 siRNA oligo Duplex | 12505 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717204 | Pre-made Cynomolgus/Rhesus macaque CD44 siRNA oligo Duplex | 717204 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098744 | Pre-made Cat/Feline CD44 siRNA oligo Duplex | 101098744 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403939 | Pre-made Dog/Canine CD44 siRNA oligo Duplex | 403939 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281057 | Pre-made Bovines/Cattle CD44 siRNA oligo Duplex | 281057 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034221 | Pre-made Equine/Horse CD44 siRNA oligo Duplex | 100034221 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD44 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T78319-Ab | Human | Anti-Human CD44 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T78319-Ab | Rat | Anti-Rat CD44 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T78319-Ab | Mouse | Anti-Mouse CD44 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T78319-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD44 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T78319-Ab | Cat/Feline | Anti-Cat/Feline CD44 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T78319-Ab | Dog/Canine | Anti-Dog/Canine CD44 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T78319-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD44 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T78319-Ab | Equine/Horse | Anti-Equine/Horse CD44 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD44 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T78319-Ag | Human | Human CD44 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T78319-Ag | Rat | Rat CD44 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T78319-Ag | Mouse | Mouse CD44 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T78319-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD44 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T78319-Ag | Cat/Feline | Cat/Feline CD44 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T78319-Ag | Dog/Canine | Dog/Canine CD44 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T78319-Ag | Bovines/Cattle | Bovines/Cattle CD44 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T78319-Ag | Equine/Horse | Equine/Horse CD44 VLP (virus-like particle) | HEK293 | Products Developing |