Explore TRPM2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2016]
| Target ID |
GM-T78205
|
| Target Name |
TRPM2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7226
|
| Gene ID |
100056810 (Equus caballus), 100856408 (Canis lupus familiaris), 101090284 (Felis catus), 28240 (Mus musculus)
294329 (Rattus norvegicus), 508029 (Bos taurus), 722161 (Macaca mulatta), 7226 (Homo sapiens)
|
| Target Alternative Names |
9830168K16Rik,EREG1,Estrogen-responsive element-associated gene 1 protein,KNP3,LTRPC2,LTrpC-2,LTrpC2),Long transient receptor potential channel 2 (LTrpC-2,NUDT9H,NUDT9L1,TRPC7,TRPM2,Transient receptor potential cation channel subfamily M member 2,Transient receptor potential channel 7 (TrpC7),Transient receptor potential melastatin 2,Trp7,Trpm2,Trpm2-predicted,Trrp7
|
| Uniprot Accession |
Q91YD4,E9PTA2,O94759
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
NOD-like receptor signaling pathway, Oxytocin signaling pathway
|
| Gene Ensembl |
ENSECAG00000023430, ENSCAFG00845020419, ENSMUSG00000009292, ENSBTAG00000021901, ENSMMUG00000004175, ENSG00000142185
|
| Target Classification |
Tumor-associated antigen (TAA)
|
TRPM2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7226 | Pre-made Human TRPM2/KNP3/EREG1 siRNA oligo Duplex | 7226 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294329 | Pre-made Rat Trpm2/Trpm2-predicted siRNA oligo Duplex | 294329 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo28240 | Pre-made Mouse Trpm2/Trp7/TRPC7 siRNA oligo Duplex | 28240 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722161 | Pre-made Cynomolgus/Rhesus macaque TRPM2 siRNA oligo Duplex | 722161 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090284 | Pre-made Cat/Feline TRPM2 siRNA oligo Duplex | 101090284 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856408 | Pre-made Dog/Canine TRPM2 siRNA oligo Duplex | 100856408 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508029 | Pre-made Bovines/Cattle TRPM2 siRNA oligo Duplex | 508029 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056810 | Pre-made Equine/Horse TRPM2 siRNA oligo Duplex | 100056810 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TRPM2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T78205-Ab | Human | Anti-Human TRPM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T78205-Ab | Rat | Anti-Rat TRPM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T78205-Ab | Mouse | Anti-Mouse TRPM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T78205-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TRPM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T78205-Ab | Cat/Feline | Anti-Cat/Feline TRPM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T78205-Ab | Dog/Canine | Anti-Dog/Canine TRPM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T78205-Ab | Bovines/Cattle | Anti-Bovines/Cattle TRPM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T78205-Ab | Equine/Horse | Anti-Equine/Horse TRPM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TRPM2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T78205-Ag | Human | Human TRPM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T78205-Ag | Rat | Rat TRPM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T78205-Ag | Mouse | Mouse TRPM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T78205-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TRPM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T78205-Ag | Cat/Feline | Cat/Feline TRPM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T78205-Ag | Dog/Canine | Dog/Canine TRPM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T78205-Ag | Bovines/Cattle | Bovines/Cattle TRPM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T78205-Ag | Equine/Horse | Equine/Horse TRPM2 VLP (virus-like particle) | HEK293 | Products Developing |
