Explore ITK gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T77537
|
| Target Name |
ITK
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3702
|
| Gene ID |
100071232 (Equus caballus), 101100785 (Felis catus), 16428 (Mus musculus), 363577 (Rattus norvegicus)
3702 (Homo sapiens), 489159 (Canis lupus familiaris), 522311 (Bos taurus), 715471 (Macaca mulatta)
|
| Target Alternative Names |
ITK,Itk,Emt,Tsk,Tcsk,EMT,LYK,LPFS1,PSCTK2
|
| Uniprot Accession |
Q03526,Q08881
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
|
| Disease |
cancer
|
| Disease from KEGG |
Chemokine signaling pathway, T cell receptor signaling pathway, Leukocyte transendothelial migration
|
| Gene Ensembl |
ENSECAG00000009530, ENSMUSG00000020395, ENSG00000113263, ENSCAFG00845002293, ENSBTAG00000000306, ENSMMUG00000010995
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of ITK cDNA Clones/ORF Plasmid
ITK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3702 | Pre-made Human ITK/EMT/LYK siRNA oligo Duplex | 3702 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363577 | Pre-made Rat Itk siRNA oligo Duplex | 363577 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16428 | Pre-made Mouse Itk/Emt/Tsk siRNA oligo Duplex | 16428 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715471 | Pre-made Cynomolgus/Rhesus macaque ITK siRNA oligo Duplex | 715471 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100785 | Pre-made Cat/Feline ITK siRNA oligo Duplex | 101100785 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489159 | Pre-made Dog/Canine ITK siRNA oligo Duplex | 489159 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo522311 | Pre-made Bovines/Cattle ITK siRNA oligo Duplex | 522311 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071232 | Pre-made Equine/Horse ITK siRNA oligo Duplex | 100071232 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ITK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T77537-Ab | Human | Anti-Human ITK monoclonal antibody | mab | | Detail |
| GM-Tg-rg-T77537-Ab | Rat | Anti-Rat ITK monoclonal antibody | mab | | Detail |
| GM-Tg-mg-T77537-Ab | Mouse | Anti-Mouse ITK monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-T77537-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ITK monoclonal antibody | mab | | Detail |
| GM-Tg-felg-T77537-Ab | Cat/Feline | Anti-Cat/Feline ITK monoclonal antibody | mab | | Detail |
| GM-Tg-cang-T77537-Ab | Dog/Canine | Anti-Dog/Canine ITK monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-T77537-Ab | Bovines/Cattle | Anti-Bovines/Cattle ITK monoclonal antibody | mab | | Detail |
| GM-Tg-equg-T77537-Ab | Equine/Horse | Anti-Equine/Horse ITK monoclonal antibody | mab | | Detail |
ITK recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T77537-Ag | Human | Human ITK recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T77537-Ag | Rat | Rat ITK recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T77537-Ag | Mouse | Mouse ITK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T77537-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ITK recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T77537-Ag | Cat/Feline | Cat/Feline ITK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T77537-Ag | Dog/Canine | Dog/Canine ITK recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T77537-Ag | Bovines/Cattle | Bovines/Cattle ITK recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T77537-Ag | Equine/Horse | Equine/Horse ITK recombinant protein | Mammalian cell | Detail |
