Explore SCN3A gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T76937
|
| Target Name |
SCN3A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6328
|
| Gene ID |
101082587 (Felis catus), 20269 (Mus musculus), 478772 (Canis lupus familiaris), 497770 (Rattus norvegicus)
6328 (Homo sapiens), 703178 (Macaca mulatta)
|
| Target Alternative Names |
DEE62,EIEE62,FFEVF4,Gm1000,NAC3,Nav1.3,SCIII,SCN3A,Scn2a,Scn3a,Sodium channel protein brain III subunit alpha,Sodium channel protein type 3 subunit alpha,Sodium channel protein type III subunit alpha,Voltage-gated sodium channel subtype III,Voltage-gated sodium channel subunit alpha Nav1.3
|
| Uniprot Accession |
A2ASI5,P08104,Q9NY46
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Taste transduction
|
| Gene Ensembl |
ENSMUSG00000057182, ENSCAFG00845015933, ENSG00000153253, ENSMMUG00000018840
|
| Target Classification |
Ion Channel
|
SCN3A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6328 | Pre-made Human SCN3A/NAC3/DEE62 siRNA oligo Duplex | 6328 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo497770 | Pre-made Rat Scn3a/SCIII/Scn2a siRNA oligo Duplex | 497770 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20269 | Pre-made Mouse Scn3a/Gm1000/Nav1.3 siRNA oligo Duplex | 20269 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703178 | Pre-made Cynomolgus/Rhesus macaque SCN3A siRNA oligo Duplex | 703178 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082587 | Pre-made Cat/Feline SCN3A siRNA oligo Duplex | 101082587 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478772 | Pre-made Dog/Canine SCN3A siRNA oligo Duplex | 478772 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
SCN3A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T76937-Ab | Human | Anti-Human SCN3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T76937-Ab | Rat | Anti-Rat SCN3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T76937-Ab | Mouse | Anti-Mouse SCN3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T76937-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SCN3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T76937-Ab | Cat/Feline | Anti-Cat/Feline SCN3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T76937-Ab | Dog/Canine | Anti-Dog/Canine SCN3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SCN3A VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T76937-Ag | Human | Human SCN3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T76937-Ag | Rat | Rat SCN3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T76937-Ag | Mouse | Mouse SCN3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T76937-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SCN3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T76937-Ag | Cat/Feline | Cat/Feline SCN3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T76937-Ag | Dog/Canine | Dog/Canine SCN3A VLP (virus-like particle) | HEK293 | Products Developing |
