Explore C1S gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]
| Target ID |
GM-T76024
|
| Target Name |
C1S
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
716
|
| Gene ID |
100060261 (Equus caballus), 101088676 (Felis catus), 192262 (Rattus norvegicus), 317677 (Mus musculus)
486714 (Canis lupus familiaris), 714589 (Macaca mulatta), 716 (Homo sapiens), 767827 (Bos taurus)
|
| Target Alternative Names |
C1 esterase,C1S,C1s,C1s2,C1sb,CC1s,Complement C1s subcomponent,Complement component 1 subcomponent s,EDSPD2,EG317677,Gm5077,r-gsp
|
| Uniprot Accession |
Q6P6T1,Q8CFG8,P09871,Q0VCX1
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
Lung Cancer
|
| Disease from KEGG |
Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection
|
| Gene Ensembl |
ENSECAG00000009519, ENSMUSG00000079343, ENSCAFG00845025415, ENSMMUG00000012786, ENSG00000182326, ENSBTAG00000004840
|
Pre-made viral vector of C1S cDNA Clones/ORF Plasmid
C1S siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo716 | Pre-made Human C1S/EDSPD2 siRNA oligo Duplex | 716 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo192262 | Pre-made Rat C1s/r-gsp siRNA oligo Duplex | 192262 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317677 | Pre-made Mouse C1s2/C1sb/Gm5077 siRNA oligo Duplex | 317677 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714589 | Pre-made Cynomolgus/Rhesus macaque C1S siRNA oligo Duplex | 714589 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088676 | Pre-made Cat/Feline C1S siRNA oligo Duplex | 101088676 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486714 | Pre-made Dog/Canine C1S siRNA oligo Duplex | 486714 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo767827 | Pre-made Bovines/Cattle C1S siRNA oligo Duplex | 767827 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060261 | Pre-made Equine/Horse C1S/CC1s siRNA oligo Duplex | 100060261 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
C1S antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T76024-Ab | Human | Anti-Human C1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T76024-Ab | Rat | Anti-Rat C1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T76024-Ab | Mouse | Anti-Mouse C1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T76024-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque C1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T76024-Ab | Cat/Feline | Anti-Cat/Feline C1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T76024-Ab | Dog/Canine | Anti-Dog/Canine C1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T76024-Ab | Bovines/Cattle | Anti-Bovines/Cattle C1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T76024-Ab | Equine/Horse | Anti-Equine/Horse C1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
C1S recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T76024-Ag | Human | Human C1S recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T76024-Ag | Rat | Rat C1S recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T76024-Ag | Mouse | Mouse C1S recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T76024-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque C1S recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T76024-Ag | Cat/Feline | Cat/Feline C1S recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T76024-Ag | Dog/Canine | Dog/Canine C1S recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T76024-Ag | Bovines/Cattle | Bovines/Cattle C1S recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T76024-Ag | Equine/Horse | Equine/Horse C1S recombinant protein | Mammalian cell | Detail |
