Explore PTGFR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T75797
|
| Target Name |
PTGFR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5737
|
| Gene ID |
100009714 (Equus caballus), 19220 (Mus musculus), 25652 (Rattus norvegicus), 282020 (Bos taurus)
479981 (Canis lupus familiaris), 493933 (Felis catus), 5737 (Homo sapiens), 707535 (Macaca mulatta)
|
| Target Alternative Names |
FP,PF2AR,PGF,PGF receptor,PGF2-alpha receptor,PTGFR,Prostaglandin F2-alpha receptor,Prostanoid FP receptor,Ptgfr,fp
|
| Uniprot Accession |
P43117,P43118,P37289,P43088
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000010558, ENSMUSG00000028036, ENSBTAG00000015902, ENSCAFG00845003039, ENSG00000122420, ENSMMUG00000010594
|
| Target Classification |
GPCR
|
PTGFR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5737 | Pre-made Human PTGFR/FP siRNA oligo Duplex | 5737 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25652 | Pre-made Rat Ptgfr/PF2AR siRNA oligo Duplex | 25652 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19220 | Pre-made Mouse Ptgfr/fp/PGF siRNA oligo Duplex | 19220 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707535 | Pre-made Cynomolgus/Rhesus macaque PTGFR siRNA oligo Duplex | 707535 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493933 | Pre-made Cat/Feline PTGFR/FP siRNA oligo Duplex | 493933 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479981 | Pre-made Dog/Canine PTGFR siRNA oligo Duplex | 479981 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282020 | Pre-made Bovines/Cattle PTGFR siRNA oligo Duplex | 282020 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009714 | Pre-made Equine/Horse PTGFR siRNA oligo Duplex | 100009714 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTGFR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T75797-Ab | Human | Anti-Human PTGFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T75797-Ab | Rat | Anti-Rat PTGFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T75797-Ab | Mouse | Anti-Mouse PTGFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T75797-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTGFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T75797-Ab | Cat/Feline | Anti-Cat/Feline PTGFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T75797-Ab | Dog/Canine | Anti-Dog/Canine PTGFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T75797-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTGFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T75797-Ab | Equine/Horse | Anti-Equine/Horse PTGFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PTGFR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T75797-Ag | Human | Human PTGFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T75797-Ag | Rat | Rat PTGFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T75797-Ag | Mouse | Mouse PTGFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T75797-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTGFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T75797-Ag | Cat/Feline | Cat/Feline PTGFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T75797-Ag | Dog/Canine | Dog/Canine PTGFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T75797-Ag | Bovines/Cattle | Bovines/Cattle PTGFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T75797-Ag | Equine/Horse | Equine/Horse PTGFR VLP (virus-like particle) | HEK293 | Products Developing |
