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Target
sublocation: Transmembrane Protein.
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T74238
|
| Target Name |
CYSLTR2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
57105
|
| Gene ID |
100056882 (Equus caballus), 102901653 (Felis catus), 170926 (Rattus norvegicus), 485445 (Canis lupus familiaris) 540387 (Bos taurus), 57105 (Homo sapiens), 70086 (Mus musculus), 705450 (Macaca mulatta)
|
| Target Alternative Names |
2300001H05Rik,CYSLT2,CYSLT2R,CYSLTR2,Cltr2,CysLTR2,Cyslt2,Cysltr2,Cysteinyl leukotriene receptor 2,G-protein coupled receptor GPCR21 (hGPCR21),G-protein coupled receptor HG57,GPCR21,HG57,HPN321,KPG_011,PSEC0146,RSBPT32,hGPCR21
|
| Uniprot Accession |
Q924T9,Q9NS75,Q920A1
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000004678, ENSCAFG00845025181, ENSBTAG00000017508, ENSG00000152207, ENSMUSG00000033470, ENSMMUG00000063377
|
| Target Classification |
GPCR
|
CYSLTR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo57105 | Pre-made Human CYSLTR2/HG57/CYSLT2 siRNA oligo Duplex | 57105 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170926 | Pre-made Rat Cysltr2/Cyslt2/RSBPT32 siRNA oligo Duplex | 170926 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo70086 | Pre-made Mouse Cysltr2/Cltr2/Cyslt2 siRNA oligo Duplex | 70086 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705450 | Pre-made Cynomolgus/Rhesus macaque CYSLTR2 siRNA oligo Duplex | 705450 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102901653 | Pre-made Cat/Feline CYSLTR2 siRNA oligo Duplex | 102901653 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485445 | Pre-made Dog/Canine CYSLTR2 siRNA oligo Duplex | 485445 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540387 | Pre-made Bovines/Cattle CYSLTR2 siRNA oligo Duplex | 540387 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056882 | Pre-made Equine/Horse CYSLTR2 siRNA oligo Duplex | 100056882 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CYSLTR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T74238-Ab | Human | Anti-Human CYSLTR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T74238-Ab | Rat | Anti-Rat CYSLTR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T74238-Ab | Mouse | Anti-Mouse CYSLTR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T74238-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CYSLTR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T74238-Ab | Cat/Feline | Anti-Cat/Feline CYSLTR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T74238-Ab | Dog/Canine | Anti-Dog/Canine CYSLTR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T74238-Ab | Bovines/Cattle | Anti-Bovines/Cattle CYSLTR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T74238-Ab | Equine/Horse | Anti-Equine/Horse CYSLTR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CYSLTR2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T74238-Ag | Human | Human CYSLTR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T74238-Ag | Rat | Rat CYSLTR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T74238-Ag | Mouse | Mouse CYSLTR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T74238-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CYSLTR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T74238-Ag | Cat/Feline | Cat/Feline CYSLTR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T74238-Ag | Dog/Canine | Dog/Canine CYSLTR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T74238-Ag | Bovines/Cattle | Bovines/Cattle CYSLTR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T74238-Ag | Equine/Horse | Equine/Horse CYSLTR2 VLP (virus-like particle) | HEK293 | Products Developing |