Explore BMI1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015]
| Target ID |
GM-T74066
|
| Target Name |
BMI1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
648
|
| Gene ID |
102148742 (Equus caballus), 106992288 (Macaca mulatta), 12151 (Mus musculus), 307151 (Rattus norvegicus)
487097 (Canis lupus familiaris), 510666 (Bos taurus), 554342 (Felis catus), 648 (Homo sapiens)
|
| Target Alternative Names |
BMI-1,BMI1,Bmi-1,Bmi1,FLVI2/BMI1,PCGF4,Pcgf4,Polycomb complex protein BMI-1,Polycomb group RING finger protein 4,RING finger protein 51,RNF51,flvi-2/bmi-1
|
| Uniprot Accession |
P25916,Q32KX7,Q9TST0,P35226
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Signaling pathways regulating pluripotency of stem cells
|
| Gene Ensembl |
ENSECAG00000019529, ENSMMUG00000000881, ENSMUSG00000026739, ENSCAFG00845008000, ENSBTAG00000015584, ENSG00000168283
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of BMI1 cDNA Clones/ORF Plasmid
BMI1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo648 | Pre-made Human BMI1/PCGF4/RNF51 siRNA oligo Duplex | 648 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo307151 | Pre-made Rat Bmi1/Pcgf4 siRNA oligo Duplex | 307151 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12151 | Pre-made Mouse Bmi1/Bmi-1/Pcgf4 siRNA oligo Duplex | 12151 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106992288 | Pre-made Cynomolgus/Rhesus macaque BMI1 siRNA oligo Duplex | 106992288 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo554342 | Pre-made Cat/Feline BMI1/BMI-1/PCGF4 siRNA oligo Duplex | 554342 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487097 | Pre-made Dog/Canine BMI1 siRNA oligo Duplex | 487097 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510666 | Pre-made Bovines/Cattle BMI1/PCGF4 siRNA oligo Duplex | 510666 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102148742 | Pre-made Equine/Horse BMI1 siRNA oligo Duplex | 102148742 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMI1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T74066-Ab | Human | Anti-Human BMI1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T74066-Ab | Rat | Anti-Rat BMI1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T74066-Ab | Mouse | Anti-Mouse BMI1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T74066-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMI1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T74066-Ab | Cat/Feline | Anti-Cat/Feline BMI1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T74066-Ab | Dog/Canine | Anti-Dog/Canine BMI1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T74066-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMI1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T74066-Ab | Equine/Horse | Anti-Equine/Horse BMI1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
BMI1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T74066-Ag | Human | Human BMI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T74066-Ag | Rat | Rat BMI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T74066-Ag | Mouse | Mouse BMI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T74066-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T74066-Ag | Cat/Feline | Cat/Feline BMI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T74066-Ag | Dog/Canine | Dog/Canine BMI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T74066-Ag | Bovines/Cattle | Bovines/Cattle BMI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T74066-Ag | Equine/Horse | Equine/Horse BMI1 recombinant protein | Mammalian cell | Detail |
