Explore CACNA1E gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
| Target ID |
GM-T73977
|
| Target Name |
CACNA1E
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
777
|
| Gene ID |
100054582 (Equus caballus), 101093985 (Felis catus), 12290 (Mus musculus), 353113 (Bos taurus)
490305 (Canis lupus familiaris), 54234 (Rattus norvegicus), 718092 (Macaca mulatta), 777 (Homo sapiens)
|
| Target Alternative Names |
A430040I15,BII,Brain calcium channel II (BII),CACH6,CACHA1E,CACNA1E,CACNL1A6,Cach6,Cacna1e,Cacnl1a6,Calcium channel,Cav2.3,Cchra1,DEE69,EIEE69,L type,Voltage-dependent R-type calcium channel subunit alpha-1E,Voltage-gated calcium channel subunit alpha Cav2.3,alpha-1 polypeptide,alpha1E,caV2.3,gm139,isoform 6
|
| Uniprot Accession |
Q61290,Q07652,Q15878
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
MAPK signaling pathway, Calcium signaling pathway, Type II diabetes mellitus
|
| Gene Ensembl |
ENSECAG00000012027, ENSMUSG00000004110, ENSBTAG00000020887, ENSCAFG00845003292, ENSMMUG00000014498, ENSG00000198216
|
| Target Classification |
Tumor-associated antigen (TAA)
|
CACNA1E siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo777 | Pre-made Human CACNA1E/BII/CACH6 siRNA oligo Duplex | 777 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54234 | Pre-made Rat Cacna1e/Cav2.3/CACHA1E siRNA oligo Duplex | 54234 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12290 | Pre-made Mouse Cacna1e/BII/Cach6 siRNA oligo Duplex | 12290 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718092 | Pre-made Cynomolgus/Rhesus macaque CACNA1E siRNA oligo Duplex | 718092 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093985 | Pre-made Cat/Feline CACNA1E siRNA oligo Duplex | 101093985 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490305 | Pre-made Dog/Canine CACNA1E siRNA oligo Duplex | 490305 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo353113 | Pre-made Bovines/Cattle CACNA1E/caV2.3 siRNA oligo Duplex | 353113 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054582 | Pre-made Equine/Horse CACNA1E siRNA oligo Duplex | 100054582 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CACNA1E antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73977-Ab | Human | Anti-Human CACNA1E monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T73977-Ab | Rat | Anti-Rat CACNA1E monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T73977-Ab | Mouse | Anti-Mouse CACNA1E monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T73977-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CACNA1E monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T73977-Ab | Cat/Feline | Anti-Cat/Feline CACNA1E monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T73977-Ab | Dog/Canine | Anti-Dog/Canine CACNA1E monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T73977-Ab | Bovines/Cattle | Anti-Bovines/Cattle CACNA1E monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73977-Ab | Equine/Horse | Anti-Equine/Horse CACNA1E monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CACNA1E VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73977-Ag | Human | Human CACNA1E VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T73977-Ag | Rat | Rat CACNA1E VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T73977-Ag | Mouse | Mouse CACNA1E VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T73977-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CACNA1E VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T73977-Ag | Cat/Feline | Cat/Feline CACNA1E VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T73977-Ag | Dog/Canine | Dog/Canine CACNA1E VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T73977-Ag | Bovines/Cattle | Bovines/Cattle CACNA1E VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T73977-Ag | Equine/Horse | Equine/Horse CACNA1E VLP (virus-like particle) | HEK293 | Products Developing |
