Explore PTK6/BRK gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
| Target ID |
GM-T73694
|
| Target Name |
PTK6/BRK
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5753
|
| Gene ID |
100060532 (Equus caballus), 101100294 (Felis catus), 20459 (Mus musculus), 366275 (Rattus norvegicus)
529814 (Bos taurus), 5753 (Homo sapiens), 719598 (Macaca mulatta)
|
| Target Alternative Names |
BRK,Breast tumor kinase,PTK6,Protein-tyrosine kinase 6,Ptk6,Sik,Tksk,Tyrosine-protein kinase BRK,tks
|
| Uniprot Accession |
Q64434,Q13882
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000009935, ENSMUSG00000038751, ENSBTAG00000044091, ENSG00000101213, ENSMMUG00000006065
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of PTK6/BRK cDNA Clones/ORF Plasmid
PTK6/BRK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5753 | Pre-made Human PTK6/BRK siRNA oligo Duplex | 5753 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo366275 | Pre-made Rat Ptk6 siRNA oligo Duplex | 366275 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20459 | Pre-made Mouse Ptk6/BRK/Sik siRNA oligo Duplex | 20459 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719598 | Pre-made Cynomolgus/Rhesus macaque PTK6 siRNA oligo Duplex | 719598 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100294 | Pre-made Cat/Feline PTK6 siRNA oligo Duplex | 101100294 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo529814 | Pre-made Bovines/Cattle PTK6 siRNA oligo Duplex | 529814 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060532 | Pre-made Equine/Horse PTK6 siRNA oligo Duplex | 100060532 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTK6/BRK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73694-Ab | Human | Anti-Human PTK6/BRK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T73694-Ab | Rat | Anti-Rat PTK6/BRK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T73694-Ab | Mouse | Anti-Mouse PTK6/BRK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T73694-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTK6/BRK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T73694-Ab | Cat/Feline | Anti-Cat/Feline PTK6/BRK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T73694-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTK6/BRK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73694-Ab | Equine/Horse | Anti-Equine/Horse PTK6/BRK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PTK6/BRK VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73694-Ag | Human | Human PTK6/BRK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T73694-Ag | Rat | Rat PTK6/BRK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T73694-Ag | Mouse | Mouse PTK6/BRK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T73694-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTK6/BRK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T73694-Ag | Cat/Feline | Cat/Feline PTK6/BRK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T73694-Ag | Bovines/Cattle | Bovines/Cattle PTK6/BRK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T73694-Ag | Equine/Horse | Equine/Horse PTK6/BRK VLP (virus-like particle) | HEK293 | Products Developing |
