Explore SETD2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
| Target ID |
GM-T73551
|
| Target Name |
SETD2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
29072
|
| Gene ID |
100064888 (Equus caballus), 101085029 (Felis catus), 235626 (Mus musculus), 29072 (Homo sapiens)
316013 (Rattus norvegicus), 476643 (Canis lupus familiaris), 539860 (Bos taurus), 711825 (Macaca mulatta)
|
| Target Alternative Names |
4921524K10Rik,HBP231,HIF-1,HIP-1,HSPC069,HYPB,Histone-lysine N-methyltransferase SETD2,Huntingtin yeast partner B,Huntingtin-interacting protein 1 (HIP-1),Huntingtin-interacting protein B,KMT3A,LLS,Lysine N-methyltransferase 3A,MRD70,Protein-lysine N-methyltransferase SETD2,RAPAS,SET domain-containing protein 2 (hSET2),SET2,SETD2,Setd2,p231HBP
|
| Uniprot Accession |
E9Q5F9,Q9BYW2
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000009721, ENSMUSG00000044791, ENSG00000181555, ENSCAFG00845009790, ENSBTAG00000002948, ENSMMUG00000021117
|
| Target Classification |
Epigenetic, Tumor-associated antigen (TAA)
|
SETD2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo29072 | Pre-made Human SETD2/LLS/HYPB siRNA oligo Duplex | 29072 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo316013 | Pre-made Rat Setd2 siRNA oligo Duplex | 316013 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo235626 | Pre-made Mouse Setd2/KMT3A/4921524K10Rik siRNA oligo Duplex | 235626 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711825 | Pre-made Cynomolgus/Rhesus macaque SETD2 siRNA oligo Duplex | 711825 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085029 | Pre-made Cat/Feline SETD2 siRNA oligo Duplex | 101085029 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476643 | Pre-made Dog/Canine SETD2 siRNA oligo Duplex | 476643 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539860 | Pre-made Bovines/Cattle SETD2 siRNA oligo Duplex | 539860 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064888 | Pre-made Equine/Horse SETD2 siRNA oligo Duplex | 100064888 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SETD2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73551-Ab | Human | Anti-Human SETD2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T73551-Ab | Rat | Anti-Rat SETD2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T73551-Ab | Mouse | Anti-Mouse SETD2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T73551-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SETD2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T73551-Ab | Cat/Feline | Anti-Cat/Feline SETD2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T73551-Ab | Dog/Canine | Anti-Dog/Canine SETD2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T73551-Ab | Bovines/Cattle | Anti-Bovines/Cattle SETD2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73551-Ab | Equine/Horse | Anti-Equine/Horse SETD2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
SETD2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73551-Ag | Human | Human SETD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T73551-Ag | Rat | Rat SETD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T73551-Ag | Mouse | Mouse SETD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T73551-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SETD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T73551-Ag | Cat/Feline | Cat/Feline SETD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T73551-Ag | Dog/Canine | Dog/Canine SETD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T73551-Ag | Bovines/Cattle | Bovines/Cattle SETD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T73551-Ag | Equine/Horse | Equine/Horse SETD2 recombinant protein | Mammalian cell | Detail |
