Explore HPN gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
| Target ID |
GM-T73471
|
| Target Name |
HPN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3249
|
| Gene ID |
100058873 (Equus caballus), 101099007 (Felis catus), 15451 (Mus musculus), 29135 (Rattus norvegicus)
3249 (Homo sapiens), 484583 (Canis lupus familiaris), 508148 (Bos taurus), 707242 (Macaca mulatta)
|
| Target Alternative Names |
HPN,Hlb320,Hpn,Serine protease hepsin,TMPRSS1,Transmembrane protease serine 1
|
| Uniprot Accession |
O35453,Q05511,P05981
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000009817, ENSMUSG00000001249, ENSG00000105707, ENSCAFG00845003738, ENSBTAG00000003829, ENSMMUG00000004844
|
HPN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3249 | Pre-made Human HPN/TMPRSS1 siRNA oligo Duplex | 3249 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29135 | Pre-made Rat Hpn siRNA oligo Duplex | 29135 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15451 | Pre-made Mouse Hpn/Hlb320 siRNA oligo Duplex | 15451 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707242 | Pre-made Cynomolgus/Rhesus macaque HPN siRNA oligo Duplex | 707242 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099007 | Pre-made Cat/Feline HPN siRNA oligo Duplex | 101099007 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484583 | Pre-made Dog/Canine HPN siRNA oligo Duplex | 484583 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508148 | Pre-made Bovines/Cattle HPN siRNA oligo Duplex | 508148 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058873 | Pre-made Equine/Horse HPN siRNA oligo Duplex | 100058873 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HPN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73471-Ab | Human | Anti-Human HPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T73471-Ab | Rat | Anti-Rat HPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T73471-Ab | Mouse | Anti-Mouse HPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T73471-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T73471-Ab | Cat/Feline | Anti-Cat/Feline HPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T73471-Ab | Dog/Canine | Anti-Dog/Canine HPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T73471-Ab | Bovines/Cattle | Anti-Bovines/Cattle HPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73471-Ab | Equine/Horse | Anti-Equine/Horse HPN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HPN VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73471-Ag | Human | Human HPN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T73471-Ag | Rat | Rat HPN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T73471-Ag | Mouse | Mouse HPN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T73471-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HPN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T73471-Ag | Cat/Feline | Cat/Feline HPN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T73471-Ag | Dog/Canine | Dog/Canine HPN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T73471-Ag | Bovines/Cattle | Bovines/Cattle HPN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T73471-Ag | Equine/Horse | Equine/Horse HPN VLP (virus-like particle) | HEK293 | Products Developing |
