Explore RRM1/RIR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
| Target ID |
GM-T73342
|
| Target Name |
RRM1/RIR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6240
|
| Gene ID |
100053126 (Equus caballus), 101097343 (Felis catus), 20133 (Mus musculus), 476823 (Canis lupus familiaris)
505537 (Bos taurus), 6240 (Homo sapiens), 685579 (Rattus norvegicus), 717990 (Macaca mulatta)
|
| Target Alternative Names |
RRM1,Rrm1,RnrM1,R1,RR1,RIR1,PEOB6
|
| Uniprot Accession |
P07742,P23921
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000023847, ENSMUSG00000030978, ENSCAFG00845011642, ENSBTAG00000013111, ENSG00000167325, ENSMMUG00000003962
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of RRM1/RIR cDNA Clones/ORF Plasmid
RRM1/RIR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6240 | Pre-made Human RRM1/R1/RR1 siRNA oligo Duplex | 6240 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo685579 | Pre-made Rat Rrm1 siRNA oligo Duplex | 685579 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20133 | Pre-made Mouse Rrm1/RnrM1 siRNA oligo Duplex | 20133 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717990 | Pre-made Cynomolgus/Rhesus macaque RRM1 siRNA oligo Duplex | 717990 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097343 | Pre-made Cat/Feline RRM1 siRNA oligo Duplex | 101097343 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476823 | Pre-made Dog/Canine RRM1 siRNA oligo Duplex | 476823 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505537 | Pre-made Bovines/Cattle RRM1 siRNA oligo Duplex | 505537 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053126 | Pre-made Equine/Horse RRM1 siRNA oligo Duplex | 100053126 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RRM1/RIR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73342-Ab | Human | Anti-Human RRM1/RIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T73342-Ab | Rat | Anti-Rat RRM1/RIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T73342-Ab | Mouse | Anti-Mouse RRM1/RIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T73342-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RRM1/RIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T73342-Ab | Cat/Feline | Anti-Cat/Feline RRM1/RIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T73342-Ab | Dog/Canine | Anti-Dog/Canine RRM1/RIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T73342-Ab | Bovines/Cattle | Anti-Bovines/Cattle RRM1/RIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73342-Ab | Equine/Horse | Anti-Equine/Horse RRM1/RIR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
RRM1/RIR VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73342-Ag | Human | Human RRM1/RIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T73342-Ag | Rat | Rat RRM1/RIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T73342-Ag | Mouse | Mouse RRM1/RIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T73342-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RRM1/RIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T73342-Ag | Cat/Feline | Cat/Feline RRM1/RIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T73342-Ag | Dog/Canine | Dog/Canine RRM1/RIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T73342-Ag | Bovines/Cattle | Bovines/Cattle RRM1/RIR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T73342-Ag | Equine/Horse | Equine/Horse RRM1/RIR VLP (virus-like particle) | HEK293 | Products Developing |
