Explore CD20/MS4A1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T73215
|
| Target Name |
CD20/MS4A1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
931
|
| Gene ID |
100059000 (Equus caballus), 12482 (Mus musculus), 309217 (Rattus norvegicus), 494216 (Felis catus) 696843 (Macaca mulatta), 931 (Homo sapiens)
|
| Target Alternative Names |
B-lymphocyte antigen CD20,B-lymphocyte surface antigen B1,B1,Bp35,CD20,CVID5,Cd20,FMC7,LEU-16,Leukocyte surface antigen Leu-16,Ly-44,MS4A1,Membrane-spanning 4-domains subfamily A member 1,Ms4a1,Ms4a2,S7
|
| Uniprot Accession |
P19437,P11836
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Hematopoietic cell lineage
|
| Gene Ensembl |
ENSECAG00000018529, ENSMUSG00000024673, ENSMMUG00000001260, ENSG00000156738
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CD20/MS4A1 cDNA Clones/ORF Plasmid
CD20/MS4A1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo931 | Pre-made Human MS4A1/B1/S7 siRNA oligo Duplex | 931 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo309217 | Pre-made Rat Ms4a1/Cd20 siRNA oligo Duplex | 309217 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12482 | Pre-made Mouse Ms4a1/Cd20/Ly-44 siRNA oligo Duplex | 12482 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696843 | Pre-made Cynomolgus/Rhesus macaque MS4A1 siRNA oligo Duplex | 696843 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo494216 | Pre-made Cat/Feline MS4A1/CD20 siRNA oligo Duplex | 494216 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059000 | Pre-made Equine/Horse MS4A1 siRNA oligo Duplex | 100059000 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD20/MS4A1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73215-Ab | Human | Anti-Human CD20/MS4A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T73215-Ab | Rat | Anti-Rat CD20/MS4A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T73215-Ab | Mouse | Anti-Mouse CD20/MS4A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T73215-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD20/MS4A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T73215-Ab | Cat/Feline | Anti-Cat/Feline CD20/MS4A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73215-Ab | Equine/Horse | Anti-Equine/Horse CD20/MS4A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD20/MS4A1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73215-Ag | Human | Human CD20/MS4A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T73215-Ag | Rat | Rat CD20/MS4A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T73215-Ag | Mouse | Mouse CD20/MS4A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T73215-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD20/MS4A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T73215-Ag | Cat/Feline | Cat/Feline CD20/MS4A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T73215-Ag | Equine/Horse | Equine/Horse CD20/MS4A1 VLP (virus-like particle) | HEK293 | Products Developing |