Explore CD116/CSF2RA gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T73097
|
| Target Name |
CD116/CSF2RA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1438
|
| Gene ID |
102148014 (Equus caballus), 1438 (Homo sapiens), 609266 (Canis lupus familiaris)
|
| Target Alternative Names |
CD116,CDw116,CSF2R,CSF2RA,CSF2RAX,CSF2RAY,CSF2RX,CSF2RY,GM-CSF-R-alpha,GMCSFR,GMCSFR-alpha,GMR,GMR-alpha,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,SMDP4,alphaGMR
|
| Uniprot Accession |
P15509
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Gene Ensembl |
ENSECAG00000016578, ENSG00000198223,ENSG00000292357, ENSCAFG00845021143
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
Pre-made viral vector of CD116/CSF2RA cDNA Clones/ORF Plasmid
CD116/CSF2RA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1438 | Pre-made Human CSF2RA/GMR/CD116 siRNA oligo Duplex | 1438 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609266 | Pre-made Dog/Canine CSF2RA siRNA oligo Duplex | 609266 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102148014 | Pre-made Equine/Horse CSF2RA siRNA oligo Duplex | 102148014 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD116/CSF2RA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73097-Ab | Human | Anti-Human CD116/CSF2RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T73097-Ab | Dog/Canine | Anti-Dog/Canine CD116/CSF2RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73097-Ab | Equine/Horse | Anti-Equine/Horse CD116/CSF2RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD116/CSF2RA VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73097-Ag | Human | Human CD116/CSF2RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T73097-Ag | Dog/Canine | Dog/Canine CD116/CSF2RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T73097-Ag | Equine/Horse | Equine/Horse CD116/CSF2RA VLP (virus-like particle) | HEK293 | Products Developing |
