Explore ROBO1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
| Target ID |
GM-T72944
|
| Target Name |
ROBO1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6091
|
| Gene ID |
100069075 (Equus caballus), 101093131 (Felis catus), 19876 (Mus musculus), 487690 (Canis lupus familiaris)
536815 (Bos taurus), 58946 (Rattus norvegicus), 6091 (Homo sapiens), 722879 (Macaca mulatta)
|
| Target Alternative Names |
CPHD8,DUTT1,Deleted in U twenty twenty,Gm310,H-Robo-1,NORS,NYS8,ROBO1,Robo1,Roundabout homolog 1,SAX3
|
| Uniprot Accession |
O89026,O55005,Q9Y6N7
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
Axon guidance
|
| Gene Ensembl |
ENSECAG00000017671, ENSMUSG00000022883, ENSCAFG00845020071, ENSBTAG00000009851, ENSG00000169855, ENSMMUG00000002327
|
| Target Classification |
Checkpoint-Immuno Oncology
|
ROBO1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6091 | Pre-made Human ROBO1/NORS/NYS8 siRNA oligo Duplex | 6091 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58946 | Pre-made Rat Robo1 siRNA oligo Duplex | 58946 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19876 | Pre-made Mouse Robo1/DUTT1/Gm310 siRNA oligo Duplex | 19876 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722879 | Pre-made Cynomolgus/Rhesus macaque ROBO1 siRNA oligo Duplex | 722879 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093131 | Pre-made Cat/Feline ROBO1 siRNA oligo Duplex | 101093131 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487690 | Pre-made Dog/Canine ROBO1 siRNA oligo Duplex | 487690 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536815 | Pre-made Bovines/Cattle ROBO1 siRNA oligo Duplex | 536815 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069075 | Pre-made Equine/Horse ROBO1 siRNA oligo Duplex | 100069075 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ROBO1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T72944-Ab | Human | Anti-Human ROBO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T72944-Ab | Rat | Anti-Rat ROBO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T72944-Ab | Mouse | Anti-Mouse ROBO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T72944-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ROBO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T72944-Ab | Cat/Feline | Anti-Cat/Feline ROBO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T72944-Ab | Dog/Canine | Anti-Dog/Canine ROBO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T72944-Ab | Bovines/Cattle | Anti-Bovines/Cattle ROBO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T72944-Ab | Equine/Horse | Anti-Equine/Horse ROBO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ROBO1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T72944-Ag | Human | Human ROBO1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T72944-Ag | Rat | Rat ROBO1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T72944-Ag | Mouse | Mouse ROBO1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T72944-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ROBO1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T72944-Ag | Cat/Feline | Cat/Feline ROBO1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T72944-Ag | Dog/Canine | Dog/Canine ROBO1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T72944-Ag | Bovines/Cattle | Bovines/Cattle ROBO1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T72944-Ag | Equine/Horse | Equine/Horse ROBO1 VLP (virus-like particle) | HEK293 | Products Developing |
