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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
| Target ID |
GM-T72849
|
| Target Name |
ARTS1/ERAP1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
51752
|
| Gene ID |
100073224 (Equus caballus), 101083063 (Felis catus), 488898 (Canis lupus familiaris), 514617 (Bos taurus) 51752 (Homo sapiens), 699996 (Macaca mulatta), 80897 (Rattus norvegicus), 80898 (Mus musculus)
|
| Target Alternative Names |
A-LAP,ALAP,APPILS,ARTS-1,ARTS1,Adipocyte-derived leucine aminopeptidase (A-LAP),Aminopeptidase PILS,Appils,Arts1,ERAAP,ERAAP1,ERAP1,Endoplasmic reticulum aminopeptidase 1,Erap1,PILS-AP,PILSA,PILSAP,Puromycin-insensitive leucyl-specific aminopeptidase (PILS-AP),Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
|
| Uniprot Accession |
Q9NZ08,Q9JJ22,Q9EQH2
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000003636, ENSCAFG00845002563, ENSBTAG00000013557, ENSG00000164307, ENSMMUG00000002063, ENSMUSG00000021583
|
Pre-made viral vector of ARTS1/ERAP1 cDNA Clones/ORF Plasmid
ARTS1/ERAP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51752 | Pre-made Human ERAP1/ALAP/A-LAP siRNA oligo Duplex | 51752 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo80897 | Pre-made Rat Erap1/Arts1/Appils siRNA oligo Duplex | 80897 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo80898 | Pre-made Mouse Erap1/A-LAP/Arts1 siRNA oligo Duplex | 80898 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699996 | Pre-made Cynomolgus/Rhesus macaque ERAP1/ARTS-1 siRNA oligo Duplex | 699996 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083063 | Pre-made Cat/Feline ERAP1 siRNA oligo Duplex | 101083063 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488898 | Pre-made Dog/Canine ERAP1 siRNA oligo Duplex | 488898 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514617 | Pre-made Bovines/Cattle ERAP1 siRNA oligo Duplex | 514617 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100073224 | Pre-made Equine/Horse ERAP1 siRNA oligo Duplex | 100073224 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ARTS1/ERAP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T72849-Ab | Human | Anti-Human ARTS1/ERAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T72849-Ab | Rat | Anti-Rat ARTS1/ERAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T72849-Ab | Mouse | Anti-Mouse ARTS1/ERAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T72849-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ARTS1/ERAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T72849-Ab | Cat/Feline | Anti-Cat/Feline ARTS1/ERAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T72849-Ab | Dog/Canine | Anti-Dog/Canine ARTS1/ERAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T72849-Ab | Bovines/Cattle | Anti-Bovines/Cattle ARTS1/ERAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T72849-Ab | Equine/Horse | Anti-Equine/Horse ARTS1/ERAP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ARTS1/ERAP1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T72849-Ag | Human | Human ARTS1/ERAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T72849-Ag | Rat | Rat ARTS1/ERAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T72849-Ag | Mouse | Mouse ARTS1/ERAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T72849-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ARTS1/ERAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T72849-Ag | Cat/Feline | Cat/Feline ARTS1/ERAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T72849-Ag | Dog/Canine | Dog/Canine ARTS1/ERAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T72849-Ag | Bovines/Cattle | Bovines/Cattle ARTS1/ERAP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T72849-Ag | Equine/Horse | Equine/Horse ARTS1/ERAP1 VLP (virus-like particle) | HEK293 | Products Developing |