Explore E-selectin/CD62E/SELE gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T72835
|
| Target Name |
E-selectin/CD62E/SELE
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6401
|
| Gene ID |
100033910 (Equus caballus), 101085520 (Felis catus), 20339 (Mus musculus), 25544 (Rattus norvegicus)
281484 (Bos taurus), 403999 (Canis lupus familiaris), 6401 (Homo sapiens), 701538 (Macaca mulatta)
|
| Target Alternative Names |
CD62 antigen-like family member E,CD62E,E-selectin,ELAM,ELAM-1,ELAM1,ESEL,Elam,Endothelial leukocyte adhesion molecule 1 (ELAM-1),LECAM2,Leukocyte-endothelial cell adhesion molecule 2 (LECAM2),SELE,Sele,selectin-e
|
| Uniprot Accession |
Q95LG1,Q00690,P98105,P98107,P33730,P16581
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Atopic Dermatitis, atopic disorders, Chronic Kidney Disease, cystic fibrosis, Inflammation, Thrombosis, breast cancer, Asthma
|
| Disease from KEGG |
Cell adhesion molecules, TNF signaling pathway, AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Malaria, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000008423, ENSMUSG00000026582, ENSBTAG00000007307, ENSCAFG00845002098, ENSG00000007908, ENSMMUG00000016580
|
Pre-made viral vector of E-selectin/CD62E/SELE cDNA Clones/ORF Plasmid
E-selectin/CD62E/SELE siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6401 | Pre-made Human SELE/ELAM/ESEL siRNA oligo Duplex | 6401 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25544 | Pre-made Rat Sele siRNA oligo Duplex | 25544 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20339 | Pre-made Mouse Sele/Elam/CD62E siRNA oligo Duplex | 20339 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701538 | Pre-made Cynomolgus/Rhesus macaque SELE siRNA oligo Duplex | 701538 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085520 | Pre-made Cat/Feline SELE siRNA oligo Duplex | 101085520 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403999 | Pre-made Dog/Canine SELE/ELAM-1/LECAM2 siRNA oligo Duplex | 403999 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281484 | Pre-made Bovines/Cattle SELE siRNA oligo Duplex | 281484 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033910 | Pre-made Equine/Horse SELE siRNA oligo Duplex | 100033910 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
E-selectin/CD62E/SELE antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T72835-Ab | Human | Anti-Human E-selectin/CD62E/SELE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T72835-Ab | Rat | Anti-Rat E-selectin/CD62E/SELE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T72835-Ab | Mouse | Anti-Mouse E-selectin/CD62E/SELE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T72835-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque E-selectin/CD62E/SELE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T72835-Ab | Cat/Feline | Anti-Cat/Feline E-selectin/CD62E/SELE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T72835-Ab | Dog/Canine | Anti-Dog/Canine E-selectin/CD62E/SELE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T72835-Ab | Bovines/Cattle | Anti-Bovines/Cattle E-selectin/CD62E/SELE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T72835-Ab | Equine/Horse | Anti-Equine/Horse E-selectin/CD62E/SELE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
E-selectin/CD62E/SELE VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T72835-Ag | Human | Human E-selectin/CD62E/SELE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T72835-Ag | Rat | Rat E-selectin/CD62E/SELE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T72835-Ag | Mouse | Mouse E-selectin/CD62E/SELE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T72835-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque E-selectin/CD62E/SELE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T72835-Ag | Cat/Feline | Cat/Feline E-selectin/CD62E/SELE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T72835-Ag | Dog/Canine | Dog/Canine E-selectin/CD62E/SELE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T72835-Ag | Bovines/Cattle | Bovines/Cattle E-selectin/CD62E/SELE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T72835-Ag | Equine/Horse | Equine/Horse E-selectin/CD62E/SELE VLP (virus-like particle) | HEK293 | Products Developing |
