Explore IL-1R1/IL1R1/CD121a gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013]
| Target ID |
GM-T72515
|
| Target Name |
IL-1R1/IL1R1/CD121a
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3554
|
| Gene ID |
100009699 (Equus caballus), 101080705 (Felis catus), 16177 (Mus musculus), 25663 (Rattus norvegicus) 3554 (Homo sapiens), 481328 (Canis lupus familiaris), 515640 (Bos taurus), 711726 (Macaca mulatta)
|
| Target Alternative Names |
CD121 antigen-like family member A,CD121A,CD121a,CD121b,CRMO3,D2S1473,IL-1R-1,IL-1R-alpha,IL-1R1,IL-1RT-1,IL-1RT1,IL-iR,IL1R,IL1R1,IL1RA,Il1r-1,Il1r1,Interleukin-1 receptor alpha (IL-1R-alpha),Interleukin-1 receptor type 1,Interleukin-1 receptor type I,P80,p80
|
| Uniprot Accession |
P13504,Q02955,P14778
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease from KEGG |
MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Hematopoietic cell lineage, Th17 cell differentiation, Inflammatory mediator regulation of TRP channels, Pathogenic Escherichia coli infection, Amoebiasis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000016394, ENSMUSG00000026072, ENSG00000115594, ENSCAFG00845010716, ENSBTAG00000005273, ENSMMUG00000020737
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
Pre-made viral vector of IL-1R1/IL1R1/CD121a cDNA Clones/ORF Plasmid
IL-1R1/IL1R1/CD121a siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3554 | Pre-made Human IL1R1/P80/IL1R siRNA oligo Duplex | 3554 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25663 | Pre-made Rat Il1r1/IL-1R-1/IL-1RT1 siRNA oligo Duplex | 25663 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16177 | Pre-made Mouse Il1r1/IL-iR/CD121a siRNA oligo Duplex | 16177 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711726 | Pre-made Cynomolgus/Rhesus macaque IL1R1 siRNA oligo Duplex | 711726 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080705 | Pre-made Cat/Feline IL1R1 siRNA oligo Duplex | 101080705 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481328 | Pre-made Dog/Canine IL1R1 siRNA oligo Duplex | 481328 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515640 | Pre-made Bovines/Cattle IL1R1 siRNA oligo Duplex | 515640 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009699 | Pre-made Equine/Horse IL1R1 siRNA oligo Duplex | 100009699 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-1R1/IL1R1/CD121a antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T72515-Ab | Human | Anti-Human IL-1R1/IL1R1/CD121a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T72515-Ab | Rat | Anti-Rat IL-1R1/IL1R1/CD121a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T72515-Ab | Mouse | Anti-Mouse IL-1R1/IL1R1/CD121a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T72515-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-1R1/IL1R1/CD121a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T72515-Ab | Cat/Feline | Anti-Cat/Feline IL-1R1/IL1R1/CD121a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T72515-Ab | Dog/Canine | Anti-Dog/Canine IL-1R1/IL1R1/CD121a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T72515-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-1R1/IL1R1/CD121a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T72515-Ab | Equine/Horse | Anti-Equine/Horse IL-1R1/IL1R1/CD121a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-1R1/IL1R1/CD121a VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T72515-Ag | Human | Human IL-1R1/IL1R1/CD121a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T72515-Ag | Rat | Rat IL-1R1/IL1R1/CD121a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T72515-Ag | Mouse | Mouse IL-1R1/IL1R1/CD121a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T72515-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-1R1/IL1R1/CD121a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T72515-Ag | Cat/Feline | Cat/Feline IL-1R1/IL1R1/CD121a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T72515-Ag | Dog/Canine | Dog/Canine IL-1R1/IL1R1/CD121a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T72515-Ag | Bovines/Cattle | Bovines/Cattle IL-1R1/IL1R1/CD121a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T72515-Ag | Equine/Horse | Equine/Horse IL-1R1/IL1R1/CD121a VLP (virus-like particle) | HEK293 | Products Developing |