Explore MC4R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010]
| Target ID |
GM-T72458
|
| Target Name |
MC4R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4160
|
| Gene ID |
100050469 (Equus caballus), 101081334 (Felis catus), 17202 (Mus musculus), 25635 (Rattus norvegicus)
281300 (Bos taurus), 4160 (Homo sapiens), 483961 (Canis lupus familiaris), 698596 (Macaca mulatta)
|
| Target Alternative Names |
BMIQ20,MC4-R,MC4R,Mc4-r,Mc4r,Melanocortin receptor 4,Pkcp
|
| Uniprot Accession |
P56450,P70596,Q9GLJ8,P32245
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000001712, ENSMUSG00000047259, ENSBTAG00000019676, ENSG00000166603, ENSCAFG00845000280, ENSMMUG00000017258
|
| Target Classification |
GPCR
|
Pre-made viral vector of MC4R cDNA Clones/ORF Plasmid
MC4R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4160 | Pre-made Human MC4R/BMIQ20 siRNA oligo Duplex | 4160 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25635 | Pre-made Rat Mc4r siRNA oligo Duplex | 25635 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17202 | Pre-made Mouse Mc4r/Pkcp/Mc4-r siRNA oligo Duplex | 17202 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698596 | Pre-made Cynomolgus/Rhesus macaque MC4R siRNA oligo Duplex | 698596 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081334 | Pre-made Cat/Feline MC4R siRNA oligo Duplex | 101081334 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483961 | Pre-made Dog/Canine MC4R siRNA oligo Duplex | 483961 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281300 | Pre-made Bovines/Cattle MC4R siRNA oligo Duplex | 281300 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050469 | Pre-made Equine/Horse MC4R siRNA oligo Duplex | 100050469 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MC4R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T72458-Ab | Human | Anti-Human MC4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T72458-Ab | Rat | Anti-Rat MC4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T72458-Ab | Mouse | Anti-Mouse MC4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T72458-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MC4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T72458-Ab | Cat/Feline | Anti-Cat/Feline MC4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T72458-Ab | Dog/Canine | Anti-Dog/Canine MC4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T72458-Ab | Bovines/Cattle | Anti-Bovines/Cattle MC4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T72458-Ab | Equine/Horse | Anti-Equine/Horse MC4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MC4R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T72458-Ag | Human | Human MC4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T72458-Ag | Rat | Rat MC4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T72458-Ag | Mouse | Mouse MC4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T72458-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MC4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T72458-Ag | Cat/Feline | Cat/Feline MC4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T72458-Ag | Dog/Canine | Dog/Canine MC4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T72458-Ag | Bovines/Cattle | Bovines/Cattle MC4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T72458-Ag | Equine/Horse | Equine/Horse MC4R VLP (virus-like particle) | HEK293 | Products Developing |
