Explore CD123/IL3RA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
| Target ID |
GM-T71377
|
| Target Name |
CD123/IL3RA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3563
|
| Gene ID |
105261394 (Felis catus), 106781070 (Equus caballus), 106995138 (Macaca mulatta), 246144 (Rattus norvegicus)
3563 (Homo sapiens), 609293 (Canis lupus familiaris)
|
| Target Alternative Names |
IL3RA,Il3ra,Cyrl,IL3R,CD123,IL3RX,IL3RY,IL3RAY,hIL-3Ra,IL-3R-alpha
|
| Uniprot Accession |
P26951
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSMMUG00000064092, ENSG00000185291,ENSG00000292332, ENSCAFG00845021612
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
Pre-made viral vector of CD123/IL3RA cDNA Clones/ORF Plasmid
CD123/IL3RA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3563 | Pre-made Human IL3RA/IL3R/CD123 siRNA oligo Duplex | 3563 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo246144 | Pre-made Rat Il3ra/Cyrl siRNA oligo Duplex | 246144 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106995138 | Pre-made Cynomolgus/Rhesus macaque IL3RA siRNA oligo Duplex | 106995138 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo105261394 | Pre-made Cat/Feline IL3RA siRNA oligo Duplex | 105261394 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609293 | Pre-made Dog/Canine IL3RA siRNA oligo Duplex | 609293 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106781070 | Pre-made Equine/Horse IL3RA siRNA oligo Duplex | 106781070 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD123/IL3RA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T71377-Ab | Human | Anti-Human CD123/IL3RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T71377-Ab | Rat | Anti-Rat CD123/IL3RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T71377-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD123/IL3RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T71377-Ab | Cat/Feline | Anti-Cat/Feline CD123/IL3RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T71377-Ab | Dog/Canine | Anti-Dog/Canine CD123/IL3RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T71377-Ab | Equine/Horse | Anti-Equine/Horse CD123/IL3RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD123/IL3RA VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T71377-Ag | Human | Human CD123/IL3RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T71377-Ag | Rat | Rat CD123/IL3RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T71377-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD123/IL3RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T71377-Ag | Cat/Feline | Cat/Feline CD123/IL3RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T71377-Ag | Dog/Canine | Dog/Canine CD123/IL3RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T71377-Ag | Equine/Horse | Equine/Horse CD123/IL3RA VLP (virus-like particle) | HEK293 | Products Developing |
