Explore IL18RAP/CD218b gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
| Target ID |
GM-T71362
|
| Target Name |
IL18RAP/CD218b
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8807
|
| Gene ID |
100050212 (Equus caballus), 101084868 (Felis catus), 16174 (Mus musculus), 373540 (Rattus norvegicus) 481327 (Canis lupus familiaris), 493716 (Bos taurus), 712046 (Macaca mulatta), 8807 (Homo sapiens)
|
| Target Alternative Names |
ACPL,AcPL,Accessory protein-like (AcPL),CD218 antigen-like family member B,CD218b,CDw218b,IL-18 receptor accessory protein,IL-18R-beta,IL-18RAcP,IL-18Rbeta,IL-18Rbeta),IL-1R accessory protein-like (IL-1RAcPL),IL-1R-7,IL-1R7,IL-1R7),IL-1RAcPL,IL18RAP,IL18RB,Il18rap,Interleukin-1 receptor 7 (IL-1R-7,Interleukin-18 receptor accessory protein,Interleukin-18 receptor accessory protein-like,Interleukin-18 receptor beta (IL-18R-beta
|
| Uniprot Accession |
Q9Z2B1,O95256
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Inflammatory bowel disease
|
| Gene Ensembl |
ENSECAG00000000214, ENSMUSG00000026068, ENSCAFG00845010356, ENSBTAG00000033748, ENSMMUG00000009246, ENSG00000115607
|
| Target Classification |
Cytokine Receptor
|
Pre-made viral vector of IL18RAP/CD218b cDNA Clones/ORF Plasmid
IL18RAP/CD218b siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8807 | Pre-made Human IL18RAP/ACPL/CD218b siRNA oligo Duplex | 8807 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo373540 | Pre-made Rat Il18rap siRNA oligo Duplex | 373540 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16174 | Pre-made Mouse Il18rap/AcPL/IL-18RAcP siRNA oligo Duplex | 16174 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712046 | Pre-made Cynomolgus/Rhesus macaque IL18RAP siRNA oligo Duplex | 712046 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084868 | Pre-made Cat/Feline IL18RAP siRNA oligo Duplex | 101084868 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481327 | Pre-made Dog/Canine IL18RAP siRNA oligo Duplex | 481327 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493716 | Pre-made Bovines/Cattle IL18RAP siRNA oligo Duplex | 493716 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050212 | Pre-made Equine/Horse IL18RAP siRNA oligo Duplex | 100050212 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL18RAP/CD218b antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T71362-Ab | Human | Anti-Human IL18RAP/CD218b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T71362-Ab | Rat | Anti-Rat IL18RAP/CD218b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T71362-Ab | Mouse | Anti-Mouse IL18RAP/CD218b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T71362-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL18RAP/CD218b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T71362-Ab | Cat/Feline | Anti-Cat/Feline IL18RAP/CD218b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T71362-Ab | Dog/Canine | Anti-Dog/Canine IL18RAP/CD218b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T71362-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL18RAP/CD218b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T71362-Ab | Equine/Horse | Anti-Equine/Horse IL18RAP/CD218b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
IL18RAP/CD218b VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T71362-Ag | Human | Human IL18RAP/CD218b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T71362-Ag | Rat | Rat IL18RAP/CD218b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T71362-Ag | Mouse | Mouse IL18RAP/CD218b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T71362-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL18RAP/CD218b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T71362-Ag | Cat/Feline | Cat/Feline IL18RAP/CD218b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T71362-Ag | Dog/Canine | Dog/Canine IL18RAP/CD218b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T71362-Ag | Bovines/Cattle | Bovines/Cattle IL18RAP/CD218b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T71362-Ag | Equine/Horse | Equine/Horse IL18RAP/CD218b VLP (virus-like particle) | HEK293 | Products Developing |