Explore CLEC12A/CD371 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]
| Target ID |
GM-T71205
|
| Target Name |
CLEC12A/CD371
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
160364
|
| Gene ID |
100053711 (Equus caballus), 101085474 (Felis catus), 160364 (Homo sapiens), 232413 (Mus musculus) 477697 (Canis lupus familiaris), 680338 (Rattus norvegicus), 722319 (Macaca mulatta)
|
| Target Alternative Names |
C-type lectin domain family 12 member A,C-type lectin-like molecule 1 (CLL-1),CD371,CLEC12A,CLL-1,CLL1,Clec12a,D230024O04,DCAL-2,Dendritic cell-associated lectin 2 (DCAL-2),KLRL1,Killer cell C-type lectin-like receptor L1 (hKLRL1),MICL,Micl,Myeloid inhibitory C-type lectin-like receptor (MICL),hKLRL1,mKLRL1,mMICL
|
| Uniprot Accession |
Q5QGZ9,Q504P2
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Gene Ensembl |
ENSECAG00000032794, ENSG00000172322, ENSMUSG00000053063, ENSCAFG00845027536, ENSMMUG00000064944
|
| Target Classification |
Checkpoint-Immuno Oncology
|
CLEC12A/CD371 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo160364 | Pre-made Human CLEC12A/CLL1/MICL siRNA oligo Duplex | 160364 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo680338 | Pre-made Rat Clec12a siRNA oligo Duplex | 680338 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo232413 | Pre-made Mouse Clec12a/Micl/CLL-1 siRNA oligo Duplex | 232413 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722319 | Pre-made Cynomolgus/Rhesus macaque CLEC12A siRNA oligo Duplex | 722319 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085474 | Pre-made Cat/Feline CLEC12A siRNA oligo Duplex | 101085474 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477697 | Pre-made Dog/Canine CLEC12A siRNA oligo Duplex | 477697 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053711 | Pre-made Equine/Horse CLEC12A siRNA oligo Duplex | 100053711 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CLEC12A/CD371 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T71205-Ab | Human | Anti-Human CLEC12A/CD371 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T71205-Ab | Rat | Anti-Rat CLEC12A/CD371 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T71205-Ab | Mouse | Anti-Mouse CLEC12A/CD371 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T71205-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CLEC12A/CD371 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T71205-Ab | Cat/Feline | Anti-Cat/Feline CLEC12A/CD371 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T71205-Ab | Dog/Canine | Anti-Dog/Canine CLEC12A/CD371 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T71205-Ab | Equine/Horse | Anti-Equine/Horse CLEC12A/CD371 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CLEC12A/CD371 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T71205-Ag | Human | Human CLEC12A/CD371 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T71205-Ag | Rat | Rat CLEC12A/CD371 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T71205-Ag | Mouse | Mouse CLEC12A/CD371 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T71205-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CLEC12A/CD371 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T71205-Ag | Cat/Feline | Cat/Feline CLEC12A/CD371 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T71205-Ag | Dog/Canine | Dog/Canine CLEC12A/CD371 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T71205-Ag | Equine/Horse | Equine/Horse CLEC12A/CD371 VLP (virus-like particle) | HEK293 | Products Developing |