Explore CYSLTR1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
| Target ID |
GM-T71192
|
| Target Name |
CYSLTR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10800
|
| Gene ID |
100072636 (Equus caballus), 100686426 (Canis lupus familiaris), 101087714 (Felis catus), 10800 (Homo sapiens)
114099 (Rattus norvegicus), 58861 (Mus musculus), 706663 (Macaca mulatta), 782045 (Bos taurus)
|
| Target Alternative Names |
CYSLT1,CYSLT1R,CYSLTR,CYSLTR1,CysLT1R,CysLTR1,Cyslt1,Cysltr1,Cysteinyl leukotriene D4 receptor (LTD4 receptor),Cysteinyl leukotriene receptor 1,G-protein coupled receptor HG55,HMTMF81
|
| Uniprot Accession |
Q9Y271,Q924T8,Q99JA4
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000007107, ENSCAFG00845020915, ENSG00000173198, ENSMUSG00000052821, ENSMMUG00000013387, ENSBTAG00000024675
|
| Target Classification |
GPCR
|
Pre-made viral vector of CYSLTR1 cDNA Clones/ORF Plasmid
CYSLTR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10800 | Pre-made Human CYSLTR1/CYSLT1/CYSLTR siRNA oligo Duplex | 10800 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114099 | Pre-made Rat Cysltr1/Cyslt1 siRNA oligo Duplex | 114099 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58861 | Pre-made Mouse Cysltr1/Cyslt1/CysLT1R siRNA oligo Duplex | 58861 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706663 | Pre-made Cynomolgus/Rhesus macaque CYSLTR1 siRNA oligo Duplex | 706663 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087714 | Pre-made Cat/Feline CYSLTR1 siRNA oligo Duplex | 101087714 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100686426 | Pre-made Dog/Canine CYSLTR1 siRNA oligo Duplex | 100686426 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo782045 | Pre-made Bovines/Cattle CYSLTR1 siRNA oligo Duplex | 782045 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072636 | Pre-made Equine/Horse CYSLTR1 siRNA oligo Duplex | 100072636 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CYSLTR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T71192-Ab | Human | Anti-Human CYSLTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T71192-Ab | Rat | Anti-Rat CYSLTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T71192-Ab | Mouse | Anti-Mouse CYSLTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T71192-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CYSLTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T71192-Ab | Cat/Feline | Anti-Cat/Feline CYSLTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T71192-Ab | Dog/Canine | Anti-Dog/Canine CYSLTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T71192-Ab | Bovines/Cattle | Anti-Bovines/Cattle CYSLTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T71192-Ab | Equine/Horse | Anti-Equine/Horse CYSLTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CYSLTR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T71192-Ag | Human | Human CYSLTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T71192-Ag | Rat | Rat CYSLTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T71192-Ag | Mouse | Mouse CYSLTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T71192-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CYSLTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T71192-Ag | Cat/Feline | Cat/Feline CYSLTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T71192-Ag | Dog/Canine | Dog/Canine CYSLTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T71192-Ag | Bovines/Cattle | Bovines/Cattle CYSLTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T71192-Ag | Equine/Horse | Equine/Horse CYSLTR1 VLP (virus-like particle) | HEK293 | Products Developing |
