Explore EphA4/EPHA4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
| Target ID |
GM-T70234
|
| Target Name |
EphA4/EPHA4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2043
|
| Gene ID |
100060325 (Equus caballus), 101081155 (Felis catus), 13838 (Mus musculus), 2043 (Homo sapiens)
316539 (Rattus norvegicus), 478925 (Canis lupus familiaris), 704857 (Macaca mulatta)
|
| Target Alternative Names |
2900005C20Rik,Cek8,EK8,EPH-like kinase 8 (EK8,EPHA4,EphA4,Epha4,Ephrin type-A receptor 4,HEK8,Hek8,RGD1560587,SEK,Sek,Sek1,TYRO1,Tyro1,Tyrosine-protein kinase TYRO1,Tyrosine-protein kinase receptor SEK,hEK8),rb
|
| Uniprot Accession |
Q03137,P54764
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Axon guidance
|
| Gene Ensembl |
ENSECAG00000012752, ENSMUSG00000026235, ENSG00000116106, ENSCAFG00845017146, ENSMMUG00000012364
|
| Target Classification |
Kinase
|
Pre-made viral vector of EphA4/EPHA4 cDNA Clones/ORF Plasmid
EphA4/EPHA4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2043 | Pre-made Human EPHA4/EK8/SEK siRNA oligo Duplex | 2043 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo316539 | Pre-made Rat Epha4/RGD1560587 siRNA oligo Duplex | 316539 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13838 | Pre-made Mouse Epha4/rb/Sek siRNA oligo Duplex | 13838 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704857 | Pre-made Cynomolgus/Rhesus macaque EPHA4 siRNA oligo Duplex | 704857 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081155 | Pre-made Cat/Feline EPHA4 siRNA oligo Duplex | 101081155 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478925 | Pre-made Dog/Canine EPHA4 siRNA oligo Duplex | 478925 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060325 | Pre-made Equine/Horse EPHA4 siRNA oligo Duplex | 100060325 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EphA4/EPHA4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T70234-Ab | Human | Anti-Human EphA4/EPHA4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T70234-Ab | Rat | Anti-Rat EphA4/EPHA4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T70234-Ab | Mouse | Anti-Mouse EphA4/EPHA4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T70234-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EphA4/EPHA4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T70234-Ab | Cat/Feline | Anti-Cat/Feline EphA4/EPHA4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T70234-Ab | Dog/Canine | Anti-Dog/Canine EphA4/EPHA4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T70234-Ab | Equine/Horse | Anti-Equine/Horse EphA4/EPHA4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EphA4/EPHA4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T70234-Ag | Human | Human EphA4/EPHA4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T70234-Ag | Rat | Rat EphA4/EPHA4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T70234-Ag | Mouse | Mouse EphA4/EPHA4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T70234-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EphA4/EPHA4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T70234-Ag | Cat/Feline | Cat/Feline EphA4/EPHA4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T70234-Ag | Dog/Canine | Dog/Canine EphA4/EPHA4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T70234-Ag | Equine/Horse | Equine/Horse EphA4/EPHA4 VLP (virus-like particle) | HEK293 | Products Developing |
