Explore NAALAD2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene is a member of the N-acetylated alpha-linked acidic dipeptidase (NAALADase) gene family. The representative member of this family is the gene encoding human prostate-specific membrane antigen (PSM), which is a marker of prostatic carcinomas and is the first to be shown to possess NAALADase activity. NAALADase cleaves N-acetyl-L-aspartate-L-glutamate (NAAG), which is a neuropeptide expressed both in the central nervous systems and in the periphery and is thought to function as a neurotransmitter. The product of this gene is a type II integral membrane protein. Transient transfection of this gene confers both NAALADase and dipetidyl peptidase IV activities to mammalian cells. This gene is highly expressed in ovary and testis as well as within discrete brain areas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Target ID |
GM-T70036
|
Target Name |
NAALAD2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10003
|
Gene ID |
10003 (Homo sapiens), 101089389 (Felis catus), 111771951 (Equus caballus), 300384 (Rattus norvegicus) 536439 (Bos taurus), 694180 (Macaca mulatta), 72560 (Mus musculus)
|
Target Alternative Names |
NAALAD2,Naalad2,GCP3,GCPIII,GPCIII,Folh1b,D9Ertd285e,NAADALASE2,NAALADASE2,2700022G20Rik
|
Uniprot Accession |
Q9Y3Q0,Q9CZR2
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
Therapeutics Target
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSG00000077616, ENSECAG00000029498,ENSECAG00000032186, ENSBTAG00000000284, ENSMMUG00000005207, ENSMUSG00000043943
|
Target Classification |
|
NAALAD2 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo10003 | Pre-made Human NAALAD2/GCP3/GCPIII siRNA oligo Duplex | 10003 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo300384 | Pre-made Rat Naalad2 siRNA oligo Duplex | 300384 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo72560 | Pre-made Mouse Naalad2/GCP3/Folh1b siRNA oligo Duplex | 72560 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo694180 | Pre-made Cynomolgus/Rhesus macaque NAALAD2 siRNA oligo Duplex | 694180 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101089389 | Pre-made Cat/Feline NAALAD2 siRNA oligo Duplex | 101089389 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo536439 | Pre-made Bovines/Cattle NAALAD2 siRNA oligo Duplex | 536439 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo111771951 | Pre-made Equine/Horse NAALAD2 siRNA oligo Duplex | 111771951 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NAALAD2 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T70036-Ab | Human | Anti-Human NAALAD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-rg-T70036-Ab | Rat | Anti-Rat NAALAD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-mg-T70036-Ab | Mouse | Anti-Mouse NAALAD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cynog-T70036-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NAALAD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-felg-T70036-Ab | Cat/Feline | Anti-Cat/Feline NAALAD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-bovg-T70036-Ab | Bovines/Cattle | Anti-Bovines/Cattle NAALAD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-equg-T70036-Ab | Equine/Horse | Anti-Equine/Horse NAALAD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
NAALAD2 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T70036-Ag | Human | Human NAALAD2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-T70036-Ag | Rat | Rat NAALAD2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-T70036-Ag | Mouse | Mouse NAALAD2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-T70036-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NAALAD2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-T70036-Ag | Cat/Feline | Cat/Feline NAALAD2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-T70036-Ag | Bovines/Cattle | Bovines/Cattle NAALAD2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-T70036-Ag | Equine/Horse | Equine/Horse NAALAD2 VLP (virus-like particle) | HEK293 | Products Developing |