Explore GRK5 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008]
| Target ID |
GM-T69612
|
| Target Name |
GRK5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2869
|
| Gene ID |
100065919 (Equus caballus), 100427251 (Macaca mulatta), 101089047 (Felis catus), 14773 (Mus musculus)
281801 (Bos taurus), 2869 (Homo sapiens), 486915 (Canis lupus familiaris), 59075 (Rattus norvegicus)
|
| Target Alternative Names |
FP2025,G protein-coupled receptor kinase 5,G protein-coupled receptor kinase GRK5,GPRK5,GRK5,Gprk5,Grk5
|
| Uniprot Accession |
Q8VEB1,P43249,P34947,Q62833
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Chemokine signaling pathway, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000023764, ENSMMUG00000004596, ENSMUSG00000003228, ENSBTAG00000007981, ENSG00000198873, ENSCAFG00845016167
|
| Target Classification |
Kinase
|
Pre-made viral vector of GRK5 cDNA Clones/ORF Plasmid
GRK5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2869 | Pre-made Human GRK5/GPRK5/FP2025 siRNA oligo Duplex | 2869 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo59075 | Pre-made Rat Grk5/Gprk5 siRNA oligo Duplex | 59075 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14773 | Pre-made Mouse Grk5/Gprk5 siRNA oligo Duplex | 14773 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100427251 | Pre-made Cynomolgus/Rhesus macaque GRK5 siRNA oligo Duplex | 100427251 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089047 | Pre-made Cat/Feline GRK5 siRNA oligo Duplex | 101089047 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486915 | Pre-made Dog/Canine GRK5 siRNA oligo Duplex | 486915 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281801 | Pre-made Bovines/Cattle GRK5/GPRK5 siRNA oligo Duplex | 281801 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065919 | Pre-made Equine/Horse GRK5 siRNA oligo Duplex | 100065919 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GRK5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T69612-Ab | Human | Anti-Human GRK5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T69612-Ab | Rat | Anti-Rat GRK5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T69612-Ab | Mouse | Anti-Mouse GRK5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T69612-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GRK5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T69612-Ab | Cat/Feline | Anti-Cat/Feline GRK5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T69612-Ab | Dog/Canine | Anti-Dog/Canine GRK5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T69612-Ab | Bovines/Cattle | Anti-Bovines/Cattle GRK5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T69612-Ab | Equine/Horse | Anti-Equine/Horse GRK5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GRK5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T69612-Ag | Human | Human GRK5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T69612-Ag | Rat | Rat GRK5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T69612-Ag | Mouse | Mouse GRK5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T69612-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GRK5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T69612-Ag | Cat/Feline | Cat/Feline GRK5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T69612-Ag | Dog/Canine | Dog/Canine GRK5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T69612-Ag | Bovines/Cattle | Bovines/Cattle GRK5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T69612-Ag | Equine/Horse | Equine/Horse GRK5 VLP (virus-like particle) | HEK293 | Products Developing |
