Explore IGFBP7 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
| Target ID |
GM-T69271
|
| Target Name |
IGFBP7
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3490
|
| Gene ID |
100033844 (Equus caballus), 101083263 (Felis catus), 289560 (Rattus norvegicus), 29817 (Mus musculus)
3490 (Homo sapiens), 608559 (Canis lupus familiaris), 616368 (Bos taurus), 693564 (Macaca mulatta)
|
| Target Alternative Names |
AGM,FSTL2,Fstl2,IBP-7,IGF-binding protein 7,IGFBP-7,IGFBP-7v,IGFBP-RP-1,IGFBP-rP1,IGFBP7,IGFBPRP1,Igfbp7,Insulin-like growth factor-binding protein 7,MAC25,MAC25 protein,Mac25,PGI2-stimulating factor,PSF,Prostacyclin-stimulating factor,RAMSVPS,TAF,Tumor-derived adhesion factor (TAF),mac25
|
| Uniprot Accession |
Q61581,Q16270
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer, Dent disease, Heart failure, Acute kidney failure
|
| Gene Ensembl |
ENSECAG00000013087, ENSMUSG00000036256, ENSG00000163453, ENSCAFG00845014179, ENSBTAG00000019368, ENSMMUG00000014011
|
Pre-made viral vector of IGFBP7 cDNA Clones/ORF Plasmid
IGFBP7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3490 | Pre-made Human IGFBP7/AGM/PSF siRNA oligo Duplex | 3490 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo289560 | Pre-made Rat Igfbp7/mac25/IGFBPRP1 siRNA oligo Duplex | 289560 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29817 | Pre-made Mouse Igfbp7/AGM/Fstl2 siRNA oligo Duplex | 29817 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693564 | Pre-made Cynomolgus/Rhesus macaque IGFBP7 siRNA oligo Duplex | 693564 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083263 | Pre-made Cat/Feline IGFBP7 siRNA oligo Duplex | 101083263 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608559 | Pre-made Dog/Canine IGFBP7 siRNA oligo Duplex | 608559 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616368 | Pre-made Bovines/Cattle IGFBP7 siRNA oligo Duplex | 616368 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033844 | Pre-made Equine/Horse IGFBP7/AGM siRNA oligo Duplex | 100033844 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IGFBP7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T69271-Ab | Human | Anti-Human IGFBP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T69271-Ab | Rat | Anti-Rat IGFBP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T69271-Ab | Mouse | Anti-Mouse IGFBP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T69271-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IGFBP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T69271-Ab | Cat/Feline | Anti-Cat/Feline IGFBP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T69271-Ab | Dog/Canine | Anti-Dog/Canine IGFBP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T69271-Ab | Bovines/Cattle | Anti-Bovines/Cattle IGFBP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T69271-Ab | Equine/Horse | Anti-Equine/Horse IGFBP7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IGFBP7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T69271-Ag | Human | Human IGFBP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T69271-Ag | Rat | Rat IGFBP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T69271-Ag | Mouse | Mouse IGFBP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T69271-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IGFBP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T69271-Ag | Cat/Feline | Cat/Feline IGFBP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T69271-Ag | Dog/Canine | Dog/Canine IGFBP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T69271-Ag | Bovines/Cattle | Bovines/Cattle IGFBP7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T69271-Ag | Equine/Horse | Equine/Horse IGFBP7 recombinant protein | Mammalian cell | Detail |
