Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Target ID GM-T69121
Target Name Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f
Gene Group ldentifer
(Target Gene ID in Homo species)
3655
Gene ID 100064056 (Equus caballus), 100856563 (Canis lupus familiaris), 101092454 (Felis catus), 114517 (Rattus norvegicus)
16403 (Mus musculus), 3655 (Homo sapiens), 535043 (Bos taurus), 697643 (Macaca mulatta)
Target Alternative Names 5033401O05Rik,CD49 antigen-like family member F,CD49f,Cd49f,ITGA6,ITGA6A,ITGA6B,Integrin alpha 6,Integrin alpha-6,Itga6,JEB6,VLA-6
Uniprot Accession Q61739,P23229
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Hematopoietic cell lineage, Regulation of actin cytoskeleton, Toxoplasmosis, Human papillomavirus infection, Pathways in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
Gene Ensembl ENSECAG00000001652, ENSCAFG00845028626, ENSMUSG00000027111, ENSG00000091409, ENSBTAG00000017266, ENSMMUG00000002370
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMPC000633Mouse Itga6/5033401O05Rik/AI115430 Mammalian (Non-Viral Vector) plasmidNM_001277970.116403MouseMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail


Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3655Pre-made Human ITGA6/JEB6/CD49f siRNA oligo Duplex3655HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo114517Pre-made Rat Itga6 siRNA oligo Duplex114517RatIn-vitro grade; in-vivo gradeDetail
pGMoligo16403Pre-made Mouse Itga6/Cd49f/VLA-6 siRNA oligo Duplex16403MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo697643Pre-made Cynomolgus/Rhesus macaque ITGA6 siRNA oligo Duplex697643Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092454Pre-made Cat/Feline ITGA6 siRNA oligo Duplex101092454Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo100856563Pre-made Dog/Canine ITGA6 siRNA oligo Duplex100856563Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo535043Pre-made Bovines/Cattle ITGA6 siRNA oligo Duplex535043Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100064056Pre-made Equine/Horse ITGA6 siRNA oligo Duplex100064056Equine/HorseIn-vitro grade; in-vivo gradeDetail


Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T69121-AbHumanAnti-Human Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T69121-AbRatAnti-Rat Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T69121-AbMouseAnti-Mouse Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T69121-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T69121-AbCat/FelineAnti-Cat/Feline Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T69121-AbDog/CanineAnti-Dog/Canine Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T69121-AbBovines/CattleAnti-Bovines/Cattle Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T69121-AbEquine/HorseAnti-Equine/Horse Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T69121-AgHumanHuman Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T69121-AgRatRat Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T69121-AgMouseMouse Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T69121-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T69121-AgCat/FelineCat/Feline Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T69121-AgDog/CanineDog/Canine Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T69121-AgBovines/CattleBovines/Cattle Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T69121-AgEquine/HorseEquine/Horse Integrin alpha 6/Integrin alpha-6/ITGA6/CD49f VLP (virus-like particle)HEK293Products Developing