Explore P2RX1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
| Target ID |
GM-T69091
|
| Target Name |
P2RX1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5023
|
| Gene ID |
100060689 (Equus caballus), 101091060 (Felis catus), 18436 (Mus musculus), 25505 (Rattus norvegicus)
491223 (Canis lupus familiaris), 5023 (Homo sapiens), 514898 (Bos taurus), 707658 (Macaca mulatta)
|
| Target Alternative Names |
ATP receptor,P2RX1,P2X purinoceptor 1,P2X1,P2XMR,P2rx1,P2x,Pdcd3,Purinergic receptor,RP-2
|
| Uniprot Accession |
P51576,P47824,P51575
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation
|
| Gene Ensembl |
ENSECAG00000009767, ENSMUSG00000020787, ENSCAFG00845017812, ENSG00000108405, ENSBTAG00000007169, ENSMMUG00000008260
|
Pre-made viral vector of P2RX1 cDNA Clones/ORF Plasmid
P2RX1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5023 | Pre-made Human P2RX1/P2X1 siRNA oligo Duplex | 5023 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25505 | Pre-made Rat P2rx1/P2XMR siRNA oligo Duplex | 25505 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18436 | Pre-made Mouse P2rx1/P2x/RP-2 siRNA oligo Duplex | 18436 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707658 | Pre-made Cynomolgus/Rhesus macaque P2RX1 siRNA oligo Duplex | 707658 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091060 | Pre-made Cat/Feline P2RX1 siRNA oligo Duplex | 101091060 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491223 | Pre-made Dog/Canine P2RX1 siRNA oligo Duplex | 491223 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514898 | Pre-made Bovines/Cattle P2RX1 siRNA oligo Duplex | 514898 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060689 | Pre-made Equine/Horse P2RX1 siRNA oligo Duplex | 100060689 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
P2RX1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T69091-Ab | Human | Anti-Human P2RX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T69091-Ab | Rat | Anti-Rat P2RX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T69091-Ab | Mouse | Anti-Mouse P2RX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T69091-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque P2RX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T69091-Ab | Cat/Feline | Anti-Cat/Feline P2RX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T69091-Ab | Dog/Canine | Anti-Dog/Canine P2RX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T69091-Ab | Bovines/Cattle | Anti-Bovines/Cattle P2RX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T69091-Ab | Equine/Horse | Anti-Equine/Horse P2RX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
P2RX1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T69091-Ag | Human | Human P2RX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T69091-Ag | Rat | Rat P2RX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T69091-Ag | Mouse | Mouse P2RX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T69091-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque P2RX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T69091-Ag | Cat/Feline | Cat/Feline P2RX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T69091-Ag | Dog/Canine | Dog/Canine P2RX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T69091-Ag | Bovines/Cattle | Bovines/Cattle P2RX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T69091-Ag | Equine/Horse | Equine/Horse P2RX1 VLP (virus-like particle) | HEK293 | Products Developing |
