Explore GRIK3/GluK3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T68876
|
| Target Name |
GRIK3/GluK3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2899
|
| Gene ID |
100069209 (Equus caballus), 101090033 (Felis catus), 14807 (Mus musculus), 2899 (Homo sapiens)
298521 (Rattus norvegicus), 532553 (Bos taurus), 608269 (Canis lupus familiaris), 713545 (Macaca mulatta)
|
| Target Alternative Names |
9630027E11,EAA5,Excitatory amino acid receptor 5 (EAA5),GLR7,GLUR7,GRIK3,GluK3,GluR7,GluR7),GluR7-3,GluR7a,Glur-7,Glur7,Glutamate receptor 7 (GluR-7,Glutamate receptor ionotropic,Grik3,gluR-7,kainate 3
|
| Uniprot Accession |
B1AS29,Q13003,P42264
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Glutamatergic synapse
|
| Gene Ensembl |
ENSECAG00000010275, ENSMUSG00000001985, ENSG00000163873, ENSBTAG00000009269, ENSCAFG00845030735
|
| Target Classification |
|
GRIK3/GluK3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2899 | Pre-made Human GRIK3/EAA5/GLR7 siRNA oligo Duplex | 2899 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo298521 | Pre-made Rat Grik3/GluK3/GluR7 siRNA oligo Duplex | 298521 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14807 | Pre-made Mouse Grik3/GluK3/Glur7 siRNA oligo Duplex | 14807 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713545 | Pre-made Cynomolgus/Rhesus macaque GRIK3 siRNA oligo Duplex | 713545 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090033 | Pre-made Cat/Feline GRIK3 siRNA oligo Duplex | 101090033 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608269 | Pre-made Dog/Canine GRIK3 siRNA oligo Duplex | 608269 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532553 | Pre-made Bovines/Cattle GRIK3 siRNA oligo Duplex | 532553 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069209 | Pre-made Equine/Horse GRIK3 siRNA oligo Duplex | 100069209 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GRIK3/GluK3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T68876-Ab | Human | Anti-Human GRIK3/GluK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T68876-Ab | Rat | Anti-Rat GRIK3/GluK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T68876-Ab | Mouse | Anti-Mouse GRIK3/GluK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T68876-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GRIK3/GluK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T68876-Ab | Cat/Feline | Anti-Cat/Feline GRIK3/GluK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T68876-Ab | Dog/Canine | Anti-Dog/Canine GRIK3/GluK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T68876-Ab | Bovines/Cattle | Anti-Bovines/Cattle GRIK3/GluK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T68876-Ab | Equine/Horse | Anti-Equine/Horse GRIK3/GluK3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GRIK3/GluK3 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T68876-Ag | Human | Human GRIK3/GluK3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T68876-Ag | Rat | Rat GRIK3/GluK3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T68876-Ag | Mouse | Mouse GRIK3/GluK3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T68876-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GRIK3/GluK3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T68876-Ag | Cat/Feline | Cat/Feline GRIK3/GluK3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T68876-Ag | Dog/Canine | Dog/Canine GRIK3/GluK3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T68876-Ag | Bovines/Cattle | Bovines/Cattle GRIK3/GluK3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T68876-Ag | Equine/Horse | Equine/Horse GRIK3/GluK3 VLP (virus-like particle) | HEK293 | Products Developing |
