Explore BMP2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]
| Target ID |
GM-T68383
|
| Target Name |
BMP2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
650
|
| Gene ID |
100051701 (Equus caballus), 100301987 (Felis catus), 12156 (Mus musculus), 29373 (Rattus norvegicus)
477162 (Canis lupus familiaris), 615037 (Bos taurus), 650 (Homo sapiens), 718330 (Macaca mulatta)
|
| Target Alternative Names |
BDA2,BMP-2,BMP2,BMP2A,Bmp2,Bmp2a,Bone morphogenetic protein 2,Bone morphogenetic protein 2A (BMP-2A),SSFSC,SSFSC1
|
| Uniprot Accession |
P21274,P49001,P12643
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Pathways in cancer, Basal cell carcinoma
|
| Gene Ensembl |
ENSECAG00000021201, ENSMUSG00000027358, ENSCAFG00845027004, ENSBTAG00000005111, ENSG00000125845, ENSMMUG00000064170
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of BMP2 cDNA Clones/ORF Plasmid
BMP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo650 | Pre-made Human BMP2/BDA2/BMP2A siRNA oligo Duplex | 650 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29373 | Pre-made Rat Bmp2 siRNA oligo Duplex | 29373 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12156 | Pre-made Mouse Bmp2/Bmp2a siRNA oligo Duplex | 12156 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718330 | Pre-made Cynomolgus/Rhesus macaque BMP2 siRNA oligo Duplex | 718330 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100301987 | Pre-made Cat/Feline BMP2 siRNA oligo Duplex | 100301987 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477162 | Pre-made Dog/Canine BMP2 siRNA oligo Duplex | 477162 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615037 | Pre-made Bovines/Cattle BMP2 siRNA oligo Duplex | 615037 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051701 | Pre-made Equine/Horse BMP2 siRNA oligo Duplex | 100051701 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMP2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T68383-Ab | Human | Anti-Human BMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T68383-Ab | Rat | Anti-Rat BMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T68383-Ab | Mouse | Anti-Mouse BMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T68383-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T68383-Ab | Cat/Feline | Anti-Cat/Feline BMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T68383-Ab | Dog/Canine | Anti-Dog/Canine BMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T68383-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T68383-Ab | Equine/Horse | Anti-Equine/Horse BMP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
BMP2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T68383-Ag | Human | Human BMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T68383-Ag | Rat | Rat BMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T68383-Ag | Mouse | Mouse BMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T68383-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T68383-Ag | Cat/Feline | Cat/Feline BMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T68383-Ag | Dog/Canine | Dog/Canine BMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T68383-Ag | Bovines/Cattle | Bovines/Cattle BMP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T68383-Ag | Equine/Horse | Equine/Horse BMP2 VLP (virus-like particle) | HEK293 | Products Developing |
