Explore LYN/JTK8 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
| Target ID |
GM-T68163
|
| Target Name |
LYN/JTK8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4067
|
| Gene ID |
100053129 (Equus caballus), 101096633 (Felis catus), 17096 (Mus musculus), 4067 (Homo sapiens)
477886 (Canis lupus familiaris), 534996 (Bos taurus), 698553 (Macaca mulatta), 81515 (Rattus norvegicus)
|
| Target Alternative Names |
Hck-2,JTK8,LYN,Lck/Yes-related novel protein tyrosine kinase,Lyn,SAIDV,Tyrosine-protein kinase Lyn,V-yes-1 Yamaguchi sarcoma viral related oncogene homolog,p53Lyn,p56Lyn
|
| Uniprot Accession |
P25911,P07948,Q07014
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Chemokine signaling pathway, NF-kappa B signaling pathway, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000012862, ENSMUSG00000042228, ENSG00000254087, ENSCAFG00845026886, ENSBTAG00000020034, ENSMMUG00000014149
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of LYN/JTK8 cDNA Clones/ORF Plasmid
LYN/JTK8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4067 | Pre-made Human LYN/JTK8/SAIDV siRNA oligo Duplex | 4067 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81515 | Pre-made Rat Lyn/p53Lyn/p56Lyn siRNA oligo Duplex | 81515 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17096 | Pre-made Mouse Lyn/Hck-2/p53Lyn siRNA oligo Duplex | 17096 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698553 | Pre-made Cynomolgus/Rhesus macaque LYN siRNA oligo Duplex | 698553 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096633 | Pre-made Cat/Feline LYN siRNA oligo Duplex | 101096633 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477886 | Pre-made Dog/Canine LYN siRNA oligo Duplex | 477886 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534996 | Pre-made Bovines/Cattle LYN siRNA oligo Duplex | 534996 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053129 | Pre-made Equine/Horse LYN siRNA oligo Duplex | 100053129 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LYN/JTK8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T68163-Ab | Human | Anti-Human LYN/JTK8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T68163-Ab | Rat | Anti-Rat LYN/JTK8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T68163-Ab | Mouse | Anti-Mouse LYN/JTK8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T68163-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LYN/JTK8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T68163-Ab | Cat/Feline | Anti-Cat/Feline LYN/JTK8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T68163-Ab | Dog/Canine | Anti-Dog/Canine LYN/JTK8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T68163-Ab | Bovines/Cattle | Anti-Bovines/Cattle LYN/JTK8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T68163-Ab | Equine/Horse | Anti-Equine/Horse LYN/JTK8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LYN/JTK8 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T68163-Ag | Human | Human LYN/JTK8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T68163-Ag | Rat | Rat LYN/JTK8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T68163-Ag | Mouse | Mouse LYN/JTK8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T68163-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LYN/JTK8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T68163-Ag | Cat/Feline | Cat/Feline LYN/JTK8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T68163-Ag | Dog/Canine | Dog/Canine LYN/JTK8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T68163-Ag | Bovines/Cattle | Bovines/Cattle LYN/JTK8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T68163-Ag | Equine/Horse | Equine/Horse LYN/JTK8 VLP (virus-like particle) | HEK293 | Products Developing |
