Explore VE-cadherin/CD144/CDH5 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015]
| Target ID |
GM-T68009
|
| Target Name |
VE-cadherin/CD144/CDH5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1003
|
| Gene ID |
100065253 (Equus caballus), 1003 (Homo sapiens), 101084501 (Felis catus), 12562 (Mus musculus) 307618 (Rattus norvegicus), 414735 (Bos taurus), 489775 (Canis lupus familiaris), 693297 (Macaca mulatta)
|
| Target Alternative Names |
7B4,7B4 antigen,CD144,CDH5,Cadherin-5,Cd144,Cdh5,VE-Cad,VE-cadherin,VECD,VEcad,Vascular endothelial cadherin (VE-cadherin),Vec
|
| Uniprot Accession |
P33151,P55284,Q6URK6
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Chronic Kidney Disease
|
| Disease from KEGG |
Cell adhesion molecules, Leukocyte transendothelial migration, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000018507, ENSG00000179776, ENSMUSG00000031871, ENSBTAG00000007421, ENSCAFG00845012097, ENSMMUG00000023525
|
Pre-made viral vector of VE-cadherin/CD144/CDH5 cDNA Clones/ORF Plasmid
VE-cadherin/CD144/CDH5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1003 | Pre-made Human CDH5/7B4/CD144 siRNA oligo Duplex | 1003 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo307618 | Pre-made Rat Cdh5 siRNA oligo Duplex | 307618 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12562 | Pre-made Mouse Cdh5/7B4/Vec siRNA oligo Duplex | 12562 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693297 | Pre-made Cynomolgus/Rhesus macaque CDH5 siRNA oligo Duplex | 693297 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084501 | Pre-made Cat/Feline CDH5 siRNA oligo Duplex | 101084501 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489775 | Pre-made Dog/Canine CDH5 siRNA oligo Duplex | 489775 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo414735 | Pre-made Bovines/Cattle CDH5 siRNA oligo Duplex | 414735 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065253 | Pre-made Equine/Horse CDH5 siRNA oligo Duplex | 100065253 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
VE-cadherin/CD144/CDH5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T68009-Ab | Human | Anti-Human VE-cadherin/CD144/CDH5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T68009-Ab | Rat | Anti-Rat VE-cadherin/CD144/CDH5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T68009-Ab | Mouse | Anti-Mouse VE-cadherin/CD144/CDH5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T68009-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque VE-cadherin/CD144/CDH5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T68009-Ab | Cat/Feline | Anti-Cat/Feline VE-cadherin/CD144/CDH5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T68009-Ab | Dog/Canine | Anti-Dog/Canine VE-cadherin/CD144/CDH5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T68009-Ab | Bovines/Cattle | Anti-Bovines/Cattle VE-cadherin/CD144/CDH5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T68009-Ab | Equine/Horse | Anti-Equine/Horse VE-cadherin/CD144/CDH5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
VE-cadherin/CD144/CDH5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T68009-Ag | Human | Human VE-cadherin/CD144/CDH5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T68009-Ag | Rat | Rat VE-cadherin/CD144/CDH5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T68009-Ag | Mouse | Mouse VE-cadherin/CD144/CDH5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T68009-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque VE-cadherin/CD144/CDH5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T68009-Ag | Cat/Feline | Cat/Feline VE-cadherin/CD144/CDH5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T68009-Ag | Dog/Canine | Dog/Canine VE-cadherin/CD144/CDH5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T68009-Ag | Bovines/Cattle | Bovines/Cattle VE-cadherin/CD144/CDH5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T68009-Ag | Equine/Horse | Equine/Horse VE-cadherin/CD144/CDH5 VLP (virus-like particle) | HEK293 | Products Developing |