Explore CD70/CD27-L gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T67805
|
| Target Name |
CD70/CD27-L
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
970
|
| Gene ID |
100065854 (Equus caballus), 101087455 (Felis catus), 21948 (Mus musculus), 301132 (Rattus norvegicus)
485018 (Canis lupus familiaris), 522074 (Bos taurus), 701080 (Macaca mulatta), 970 (Homo sapiens)
|
| Target Alternative Names |
CD27 ligand (CD27-L),CD27-L,CD27L,CD27LG,CD70,CD70 antigen,Cd27l,Cd70,LPFS3,TNFSF7,TNLG8A,Tnfsf7,Tnlg8a,Tumor necrosis factor ligand superfamily member 7
|
| Uniprot Accession |
O55237,P32970
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSMUSG00000019489, ENSCAFG00845010526, ENSBTAG00000009752, ENSMMUG00000011042, ENSG00000125726
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CD70/CD27-L cDNA Clones/ORF Plasmid
CD70/CD27-L siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo970 | Pre-made Human CD70/CD27L/LPFS3 siRNA oligo Duplex | 970 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo301132 | Pre-made Rat Cd70 siRNA oligo Duplex | 301132 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21948 | Pre-made Mouse Cd70/Cd27l/CD27LG siRNA oligo Duplex | 21948 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701080 | Pre-made Cynomolgus/Rhesus macaque CD70/TNFSF7/TNLG8A siRNA oligo Duplex | 701080 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087455 | Pre-made Cat/Feline CD70 siRNA oligo Duplex | 101087455 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485018 | Pre-made Dog/Canine CD70 siRNA oligo Duplex | 485018 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo522074 | Pre-made Bovines/Cattle CD70/TNLG8A siRNA oligo Duplex | 522074 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065854 | Pre-made Equine/Horse CD70/TNLG8A siRNA oligo Duplex | 100065854 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD70/CD27-L antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T67805-Ab | Human | Anti-Human CD70/CD27-L monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T67805-Ab | Rat | Anti-Rat CD70/CD27-L monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T67805-Ab | Mouse | Anti-Mouse CD70/CD27-L monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T67805-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD70/CD27-L monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T67805-Ab | Cat/Feline | Anti-Cat/Feline CD70/CD27-L monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T67805-Ab | Dog/Canine | Anti-Dog/Canine CD70/CD27-L monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T67805-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD70/CD27-L monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T67805-Ab | Equine/Horse | Anti-Equine/Horse CD70/CD27-L monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
CD70/CD27-L VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T67805-Ag | Human | Human CD70/CD27-L VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T67805-Ag | Rat | Rat CD70/CD27-L VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T67805-Ag | Mouse | Mouse CD70/CD27-L VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T67805-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD70/CD27-L VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T67805-Ag | Cat/Feline | Cat/Feline CD70/CD27-L VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T67805-Ag | Dog/Canine | Dog/Canine CD70/CD27-L VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T67805-Ag | Bovines/Cattle | Bovines/Cattle CD70/CD27-L VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T67805-Ag | Equine/Horse | Equine/Horse CD70/CD27-L VLP (virus-like particle) | HEK293 | Products Developing |
