Explore Nurr1/NR4A2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T67163
|
| Target Name |
Nurr1/NR4A2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4929
|
| Gene ID |
100050666 (Equus caballus), 101089537 (Felis catus), 18227 (Mus musculus), 478754 (Canis lupus familiaris) 4929 (Homo sapiens), 540245 (Bos taurus), 54278 (Rattus norvegicus), 697077 (Macaca mulatta)
|
| Target Alternative Names |
HZF-3,IDLDP,Immediate-early response protein NOT,NOT,NR4A2,NURR1,Nr4a2,Nuclear receptor subfamily 4 group A member 2,Nurr1,Orphan nuclear receptor NURR1,RNR-1,RNR1,TINOR,TINUR,Transcriptionally-inducible nuclear receptor
|
| Uniprot Accession |
Q06219,P43354,Q08E53,Q07917
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Aldosterone synthesis and secretion, Parathyroid hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSECAG00000014232, ENSMUSG00000026826, ENSCAFG00845025175, ENSG00000153234, ENSBTAG00000003650, ENSMMUG00000011607
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of Nurr1/NR4A2 cDNA Clones/ORF Plasmid
Nurr1/NR4A2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4929 | Pre-made Human NR4A2/NOT/RNR1 siRNA oligo Duplex | 4929 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54278 | Pre-made Rat Nr4a2/RNR1/Nurr1 siRNA oligo Duplex | 54278 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18227 | Pre-made Mouse Nr4a2/NOT/HZF-3 siRNA oligo Duplex | 18227 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697077 | Pre-made Cynomolgus/Rhesus macaque NR4A2 siRNA oligo Duplex | 697077 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089537 | Pre-made Cat/Feline NR4A2 siRNA oligo Duplex | 101089537 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478754 | Pre-made Dog/Canine NR4A2 siRNA oligo Duplex | 478754 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540245 | Pre-made Bovines/Cattle NR4A2 siRNA oligo Duplex | 540245 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050666 | Pre-made Equine/Horse NR4A2 siRNA oligo Duplex | 100050666 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Nurr1/NR4A2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T67163-Ab | Human | Anti-Human Nurr1/NR4A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T67163-Ab | Rat | Anti-Rat Nurr1/NR4A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T67163-Ab | Mouse | Anti-Mouse Nurr1/NR4A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T67163-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Nurr1/NR4A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T67163-Ab | Cat/Feline | Anti-Cat/Feline Nurr1/NR4A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T67163-Ab | Dog/Canine | Anti-Dog/Canine Nurr1/NR4A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T67163-Ab | Bovines/Cattle | Anti-Bovines/Cattle Nurr1/NR4A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T67163-Ab | Equine/Horse | Anti-Equine/Horse Nurr1/NR4A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
Nurr1/NR4A2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T67163-Ag | Human | Human Nurr1/NR4A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T67163-Ag | Rat | Rat Nurr1/NR4A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T67163-Ag | Mouse | Mouse Nurr1/NR4A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T67163-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Nurr1/NR4A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T67163-Ag | Cat/Feline | Cat/Feline Nurr1/NR4A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T67163-Ag | Dog/Canine | Dog/Canine Nurr1/NR4A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T67163-Ag | Bovines/Cattle | Bovines/Cattle Nurr1/NR4A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T67163-Ag | Equine/Horse | Equine/Horse Nurr1/NR4A2 recombinant protein | Mammalian cell | Detail |