Explore DRD2/D2R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T67162
|
| Target Name |
DRD2/D2R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1813
|
| Gene ID |
100062195 (Equus caballus), 101096838 (Felis catus), 13489 (Mus musculus), 1813 (Homo sapiens)
24318 (Rattus norvegicus), 281126 (Bos taurus), 403701 (Canis lupus familiaris), 694181 (Macaca mulatta)
|
| Target Alternative Names |
D(2) dopamine receptor,D2DR,D2R,DRD2,Dopamine D2 receptor,Drd-2,Drd2
|
| Uniprot Accession |
P61168,P14416,P61169,P20288,Q9GJU1
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Cocaine addiction
|
| Gene Ensembl |
ENSECAG00000013567, ENSMUSG00000032259, ENSG00000149295, ENSBTAG00000010860, ENSCAFG00845000700, ENSMMUG00000014334
|
| Target Classification |
GPCR, Tumor-associated antigen (TAA)
|
Pre-made viral vector of DRD2/D2R cDNA Clones/ORF Plasmid
DRD2/D2R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1813 | Pre-made Human DRD2/D2R/D2DR siRNA oligo Duplex | 1813 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24318 | Pre-made Rat Drd2 siRNA oligo Duplex | 24318 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13489 | Pre-made Mouse Drd2/D2R/Drd-2 siRNA oligo Duplex | 13489 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694181 | Pre-made Cynomolgus/Rhesus macaque DRD2 siRNA oligo Duplex | 694181 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096838 | Pre-made Cat/Feline DRD2 siRNA oligo Duplex | 101096838 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403701 | Pre-made Dog/Canine DRD2 siRNA oligo Duplex | 403701 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281126 | Pre-made Bovines/Cattle DRD2 siRNA oligo Duplex | 281126 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062195 | Pre-made Equine/Horse DRD2 siRNA oligo Duplex | 100062195 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DRD2/D2R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T67162-Ab | Human | Anti-Human DRD2/D2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T67162-Ab | Rat | Anti-Rat DRD2/D2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T67162-Ab | Mouse | Anti-Mouse DRD2/D2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T67162-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DRD2/D2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T67162-Ab | Cat/Feline | Anti-Cat/Feline DRD2/D2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T67162-Ab | Dog/Canine | Anti-Dog/Canine DRD2/D2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T67162-Ab | Bovines/Cattle | Anti-Bovines/Cattle DRD2/D2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T67162-Ab | Equine/Horse | Anti-Equine/Horse DRD2/D2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
DRD2/D2R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T67162-Ag | Human | Human DRD2/D2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T67162-Ag | Rat | Rat DRD2/D2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T67162-Ag | Mouse | Mouse DRD2/D2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T67162-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DRD2/D2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T67162-Ag | Cat/Feline | Cat/Feline DRD2/D2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T67162-Ag | Dog/Canine | Dog/Canine DRD2/D2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T67162-Ag | Bovines/Cattle | Bovines/Cattle DRD2/D2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T67162-Ag | Equine/Horse | Equine/Horse DRD2/D2R VLP (virus-like particle) | HEK293 | Products Developing |
