Explore Integrin Alpha V/ITGAV/CD51 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
| Target ID |
GM-T67103
|
| Target Name |
Integrin Alpha V/ITGAV/CD51
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3685
|
| Gene ID |
100068706 (Equus caballus), 101085820 (Felis catus), 16410 (Mus musculus), 281875 (Bos taurus)
296456 (Rattus norvegicus), 3685 (Homo sapiens), 488437 (Canis lupus familiaris), 707756 (Macaca mulatta)
|
| Target Alternative Names |
1110004F14Rik,2610028E01Rik,CD51,Cd51,D430040G12Rik,ITGAV,Integrin Alpha V,Integrin alpha-V,Itgav,MSK8,VNRA,VTNR,Vitronectin receptor,Vitronectin receptor subunit alpha
|
| Uniprot Accession |
P43406,P80746,P06756
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease from KEGG |
Phagosome, PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000021377, ENSMUSG00000027087, ENSBTAG00000019929, ENSG00000138448, ENSCAFG00845017805, ENSMMUG00000019462
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Integrin Alpha V/ITGAV/CD51 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3685 | Pre-made Human ITGAV/CD51/MSK8 siRNA oligo Duplex | 3685 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo296456 | Pre-made Rat Itgav/Cd51 siRNA oligo Duplex | 296456 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16410 | Pre-made Mouse Itgav/CD51/1110004F14Rik siRNA oligo Duplex | 16410 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707756 | Pre-made Cynomolgus/Rhesus macaque ITGAV siRNA oligo Duplex | 707756 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085820 | Pre-made Cat/Feline ITGAV siRNA oligo Duplex | 101085820 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488437 | Pre-made Dog/Canine ITGAV siRNA oligo Duplex | 488437 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281875 | Pre-made Bovines/Cattle ITGAV siRNA oligo Duplex | 281875 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068706 | Pre-made Equine/Horse ITGAV siRNA oligo Duplex | 100068706 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Integrin Alpha V/ITGAV/CD51 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T67103-Ab | Human | Anti-Human Integrin Alpha V/ITGAV/CD51 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T67103-Ab | Rat | Anti-Rat Integrin Alpha V/ITGAV/CD51 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T67103-Ab | Mouse | Anti-Mouse Integrin Alpha V/ITGAV/CD51 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T67103-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Integrin Alpha V/ITGAV/CD51 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T67103-Ab | Cat/Feline | Anti-Cat/Feline Integrin Alpha V/ITGAV/CD51 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T67103-Ab | Dog/Canine | Anti-Dog/Canine Integrin Alpha V/ITGAV/CD51 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T67103-Ab | Bovines/Cattle | Anti-Bovines/Cattle Integrin Alpha V/ITGAV/CD51 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T67103-Ab | Equine/Horse | Anti-Equine/Horse Integrin Alpha V/ITGAV/CD51 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Integrin Alpha V/ITGAV/CD51 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T67103-Ag | Human | Human Integrin Alpha V/ITGAV/CD51 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T67103-Ag | Rat | Rat Integrin Alpha V/ITGAV/CD51 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T67103-Ag | Mouse | Mouse Integrin Alpha V/ITGAV/CD51 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T67103-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Integrin Alpha V/ITGAV/CD51 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T67103-Ag | Cat/Feline | Cat/Feline Integrin Alpha V/ITGAV/CD51 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T67103-Ag | Dog/Canine | Dog/Canine Integrin Alpha V/ITGAV/CD51 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T67103-Ag | Bovines/Cattle | Bovines/Cattle Integrin Alpha V/ITGAV/CD51 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T67103-Ag | Equine/Horse | Equine/Horse Integrin Alpha V/ITGAV/CD51 VLP (virus-like particle) | HEK293 | Products Developing |
