Explore Cathepsin D/CTSD gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
| Target ID |
GM-T67102
|
| Target Name |
Cathepsin D/CTSD
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1509
|
| Gene ID |
100629639 (Equus caballus), 101094625 (Felis catus), 13033 (Mus musculus), 1509 (Homo sapiens)
171293 (Rattus norvegicus), 282883 (Bos taurus), 483662 (Canis lupus familiaris), 703534 (Macaca mulatta)
|
| Target Alternative Names |
CATD,CD,CLN10,CPSD,CTSD,CatD,Cathepsin D,Ctsd,HEL-S-130P
|
| Uniprot Accession |
P18242,P07339,P24268,P80209,Q4LAL9
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer, colorectal cancer, Malignant neoplasm of bladder
|
| Disease from KEGG |
Sphingolipid signaling pathway, Lysosome, Apoptosis, Tuberculosis
|
| Gene Ensembl |
ENSMUSG00000007891, ENSG00000117984, ENSBTAG00000007622, ENSCAFG00845009905, ENSMMUG00000003874
|
Pre-made viral vector of Cathepsin D/CTSD cDNA Clones/ORF Plasmid
Cathepsin D/CTSD siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1509 | Pre-made Human CTSD/CPSD/CLN10 siRNA oligo Duplex | 1509 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171293 | Pre-made Rat Ctsd siRNA oligo Duplex | 171293 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13033 | Pre-made Mouse Ctsd/CD/CatD siRNA oligo Duplex | 13033 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703534 | Pre-made Cynomolgus/Rhesus macaque CTSD siRNA oligo Duplex | 703534 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094625 | Pre-made Cat/Feline CTSD siRNA oligo Duplex | 101094625 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483662 | Pre-made Dog/Canine CTSD siRNA oligo Duplex | 483662 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282883 | Pre-made Bovines/Cattle CTSD/CATD siRNA oligo Duplex | 282883 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100629639 | Pre-made Equine/Horse CTSD siRNA oligo Duplex | 100629639 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cathepsin D/CTSD antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T67102-Ab | Human | Anti-Human Cathepsin D/CTSD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T67102-Ab | Rat | Anti-Rat Cathepsin D/CTSD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T67102-Ab | Mouse | Anti-Mouse Cathepsin D/CTSD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T67102-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cathepsin D/CTSD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T67102-Ab | Cat/Feline | Anti-Cat/Feline Cathepsin D/CTSD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T67102-Ab | Dog/Canine | Anti-Dog/Canine Cathepsin D/CTSD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T67102-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cathepsin D/CTSD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T67102-Ab | Equine/Horse | Anti-Equine/Horse Cathepsin D/CTSD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Cathepsin D/CTSD recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T67102-Ag | Human | Human Cathepsin D/CTSD recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T67102-Ag | Rat | Rat Cathepsin D/CTSD recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T67102-Ag | Mouse | Mouse Cathepsin D/CTSD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T67102-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cathepsin D/CTSD recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T67102-Ag | Cat/Feline | Cat/Feline Cathepsin D/CTSD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T67102-Ag | Dog/Canine | Dog/Canine Cathepsin D/CTSD recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T67102-Ag | Bovines/Cattle | Bovines/Cattle Cathepsin D/CTSD recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T67102-Ag | Equine/Horse | Equine/Horse Cathepsin D/CTSD recombinant protein | Mammalian cell | Detail |
