Explore KCNMB4/BKbeta4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T67063
|
| Target Name |
KCNMB4/BKbeta4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
27345
|
| Gene ID |
100063351 (Equus caballus), 101101646 (Felis catus), 27345 (Homo sapiens), 474447 (Canis lupus familiaris)
520448 (Bos taurus), 58802 (Mus musculus), 66016 (Rattus norvegicus), 717360 (Macaca mulatta)
|
| Target Alternative Names |
1700058G18Rik,2900045G12Rik,BK channel subunit beta-4 (BKbeta4,BKbeta4,Calcium-activated potassium channel,Calcium-activated potassium channel subunit beta-4,Charybdotoxin receptor subunit beta-4,Hbeta4),K(VCA)beta-4,KCNMB4,Kcnmb4,Maxi K channel subunit beta-4,Slo-beta-4,k(VCA)beta-4,slo-beta-4,subfamily M subunit beta-4
|
| Uniprot Accession |
Q86W47,Q9JIN6,Q9ESK8
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Insulin secretion
|
| Gene Ensembl |
ENSECAG00000013805, ENSG00000135643, ENSCAFG00845019977, ENSBTAG00000003749, ENSMUSG00000054934
|
KCNMB4/BKbeta4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27345 | Pre-made Human KCNMB4 siRNA oligo Duplex | 27345 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo66016 | Pre-made Rat Kcnmb4 siRNA oligo Duplex | 66016 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58802 | Pre-made Mouse Kcnmb4/BKbeta4/slo-beta-4 siRNA oligo Duplex | 58802 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717360 | Pre-made Cynomolgus/Rhesus macaque KCNMB4 siRNA oligo Duplex | 717360 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101646 | Pre-made Cat/Feline KCNMB4 siRNA oligo Duplex | 101101646 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474447 | Pre-made Dog/Canine KCNMB4 siRNA oligo Duplex | 474447 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520448 | Pre-made Bovines/Cattle KCNMB4 siRNA oligo Duplex | 520448 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063351 | Pre-made Equine/Horse KCNMB4 siRNA oligo Duplex | 100063351 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNMB4/BKbeta4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T67063-Ab | Human | Anti-Human KCNMB4/BKbeta4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T67063-Ab | Rat | Anti-Rat KCNMB4/BKbeta4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T67063-Ab | Mouse | Anti-Mouse KCNMB4/BKbeta4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T67063-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNMB4/BKbeta4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T67063-Ab | Cat/Feline | Anti-Cat/Feline KCNMB4/BKbeta4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T67063-Ab | Dog/Canine | Anti-Dog/Canine KCNMB4/BKbeta4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T67063-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNMB4/BKbeta4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T67063-Ab | Equine/Horse | Anti-Equine/Horse KCNMB4/BKbeta4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KCNMB4/BKbeta4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T67063-Ag | Human | Human KCNMB4/BKbeta4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T67063-Ag | Rat | Rat KCNMB4/BKbeta4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T67063-Ag | Mouse | Mouse KCNMB4/BKbeta4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T67063-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNMB4/BKbeta4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T67063-Ag | Cat/Feline | Cat/Feline KCNMB4/BKbeta4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T67063-Ag | Dog/Canine | Dog/Canine KCNMB4/BKbeta4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T67063-Ag | Bovines/Cattle | Bovines/Cattle KCNMB4/BKbeta4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T67063-Ag | Equine/Horse | Equine/Horse KCNMB4/BKbeta4 VLP (virus-like particle) | HEK293 | Products Developing |
