Explore SMO gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010]
| Target ID |
GM-T66505
|
| Target Name |
SMO
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6608
|
| Gene ID |
100033990 (Equus caballus), 101087567 (Felis catus), 25273 (Rattus norvegicus), 319757 (Mus musculus)
482262 (Canis lupus familiaris), 539308 (Bos taurus), 6608 (Homo sapiens), 701334 (Macaca mulatta)
|
| Target Alternative Names |
CRJS,E130215L21Rik,FZD11,Gx,PHLS,Protein Gx,Protein smoothened,SMO,SMOH,Smo,Smoh,bnb,smoothened
|
| Uniprot Accession |
P97698,P56726,Q99835
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Non-Small Cell Lung Cancer
|
| Disease from KEGG |
Axon guidance, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma
|
| Gene Ensembl |
ENSECAG00000004904, ENSMUSG00000001761, ENSCAFG00845020728, ENSBTAG00000013287, ENSG00000128602, ENSMMUG00000012110
|
| Target Classification |
GPCR
|
Pre-made viral vector of SMO cDNA Clones/ORF Plasmid
SMO siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6608 | Pre-made Human SMO/Gx/CRJS siRNA oligo Duplex | 6608 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25273 | Pre-made Rat Smo/Smoh siRNA oligo Duplex | 25273 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo319757 | Pre-made Mouse Smo/bnb/Smoh siRNA oligo Duplex | 319757 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701334 | Pre-made Cynomolgus/Rhesus macaque SMO siRNA oligo Duplex | 701334 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087567 | Pre-made Cat/Feline SMO siRNA oligo Duplex | 101087567 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482262 | Pre-made Dog/Canine SMO siRNA oligo Duplex | 482262 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539308 | Pre-made Bovines/Cattle SMO siRNA oligo Duplex | 539308 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033990 | Pre-made Equine/Horse SMO siRNA oligo Duplex | 100033990 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SMO antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T66505-Ab | Human | Anti-Human SMO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T66505-Ab | Rat | Anti-Rat SMO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T66505-Ab | Mouse | Anti-Mouse SMO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T66505-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SMO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T66505-Ab | Cat/Feline | Anti-Cat/Feline SMO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T66505-Ab | Dog/Canine | Anti-Dog/Canine SMO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T66505-Ab | Bovines/Cattle | Anti-Bovines/Cattle SMO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T66505-Ab | Equine/Horse | Anti-Equine/Horse SMO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SMO VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T66505-Ag | Human | Human SMO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T66505-Ag | Rat | Rat SMO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T66505-Ag | Mouse | Mouse SMO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T66505-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SMO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T66505-Ag | Cat/Feline | Cat/Feline SMO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T66505-Ag | Dog/Canine | Dog/Canine SMO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T66505-Ag | Bovines/Cattle | Bovines/Cattle SMO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T66505-Ag | Equine/Horse | Equine/Horse SMO VLP (virus-like particle) | HEK293 | Products Developing |
