Explore EIF2AK4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]
| Target ID |
GM-T66396
|
| Target Name |
EIF2AK4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
440275
|
| Gene ID |
100071494 (Equus caballus), 100428309 (Macaca mulatta), 101087928 (Felis catus), 114859 (Rattus norvegicus)
27103 (Mus musculus), 440275 (Homo sapiens), 478257 (Canis lupus familiaris), 513829 (Bos taurus)
|
| Target Alternative Names |
2610011M03,EIF2AK4,Eif2ak4,Eukaryotic translation initiation factor 2-alpha kinase 4,GCN2,GCN2-like protein,Gcn2-like,MGCN2,PVOD2,eIF-2-alpha kinase GCN2
|
| Uniprot Accession |
D4A7V9,Q9QZ05,Q9P2K8
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Protein processing in endoplasmic reticulum, Hepatitis C, Measles
|
| Gene Ensembl |
ENSECAG00000000348, ENSMMUG00000038966, ENSMUSG00000005102, ENSG00000128829, ENSBTAG00000014351
|
| Target Classification |
Kinase
|
EIF2AK4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo440275 | Pre-made Human EIF2AK4/GCN2/PVOD2 siRNA oligo Duplex | 440275 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114859 | Pre-made Rat Eif2ak4 siRNA oligo Duplex | 114859 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo27103 | Pre-made Mouse Eif2ak4/GCN2/MGCN2 siRNA oligo Duplex | 27103 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100428309 | Pre-made Cynomolgus/Rhesus macaque EIF2AK4 siRNA oligo Duplex | 100428309 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087928 | Pre-made Cat/Feline EIF2AK4 siRNA oligo Duplex | 101087928 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478257 | Pre-made Dog/Canine EIF2AK4 siRNA oligo Duplex | 478257 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo513829 | Pre-made Bovines/Cattle EIF2AK4/Gcn2-like siRNA oligo Duplex | 513829 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071494 | Pre-made Equine/Horse EIF2AK4 siRNA oligo Duplex | 100071494 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EIF2AK4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T66396-Ab | Human | Anti-Human EIF2AK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T66396-Ab | Rat | Anti-Rat EIF2AK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T66396-Ab | Mouse | Anti-Mouse EIF2AK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T66396-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EIF2AK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T66396-Ab | Cat/Feline | Anti-Cat/Feline EIF2AK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T66396-Ab | Dog/Canine | Anti-Dog/Canine EIF2AK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T66396-Ab | Bovines/Cattle | Anti-Bovines/Cattle EIF2AK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T66396-Ab | Equine/Horse | Anti-Equine/Horse EIF2AK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
EIF2AK4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T66396-Ag | Human | Human EIF2AK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T66396-Ag | Rat | Rat EIF2AK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T66396-Ag | Mouse | Mouse EIF2AK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T66396-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EIF2AK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T66396-Ag | Cat/Feline | Cat/Feline EIF2AK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T66396-Ag | Dog/Canine | Dog/Canine EIF2AK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T66396-Ag | Bovines/Cattle | Bovines/Cattle EIF2AK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T66396-Ag | Equine/Horse | Equine/Horse EIF2AK4 recombinant protein | Mammalian cell | Detail |
